Mini radial keratotomy reduces ocular integrity: Axial compression in a postmortem porcine eye model

Thomas L. Steinemann, Tracy C. Baltz, Byron L. Lam, Michael Soulsby, Robert C. Walls, Harry H. Brown

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Objective: This study aimed to examine ocular rupture force in pig eyes after 'minimally invasive radial keratotomy' (MRK) and standard radial keratotomy (SRK). Design: Experimental study. Materials: A total of 71 pairs of pig eyes (51 control eyes) were examined. Intervention: An axial-torsional Materials Testing System (MTS, Eden Prairie, MN) was used to apply blunt force to the corneal surface. A force transducer measured the rupture forces in control eyes and in eyes with MRK or SRK. Five groups of paired eyes were compared: 2.0-mm MRK versus control (N = 12), 3.5-mm MRK versus control (N = 21), 6.5-mm SRK versus control (N = 18), SRK versus 3.5-mm MRK (N = 10), and 3.5-mm MRK versus 2.0-mm MRK (N = 10). Main Outcome Measure: Ocular rupture force (newtons) was measured. Results: The mean rupture force in newtons was 746.3 for control eyes, 514.2 for 2.0-mm MRK, 353.1 for 3.5-mm MRK, and 246.2 for SRK. Analysis of variance showed a statistically significant difference (P ≤ 0.04) between paired comparisons. Conclusion: The MRK and SRK significantly weakened ocular integrity compared with control eyes not operated on. MRK required significantly more force to rupture than SRK. MRK eyes, however, ruptured at 50% to 70% of the force required to rupture eyes not operated on. Any patient considering radial keratotomy should be counseled about the risk of greater ocular damage in trauma.

Original languageEnglish (US)
Pages (from-to)1739-1744
Number of pages6
Issue number9
StatePublished - Sep 1 1998

ASJC Scopus subject areas

  • Ophthalmology


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