Microsurgical epididymal sperm aspiration: Indications, techniques and outcomes

Aaron M. Bernie, Ranjith Ramasamy, Doron S. Stember, Peter J. Stahl

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Microsurgical epididymal sperm aspiration (MESA) refers to retrieval of sperm-containing fluid from optimal areas of the epididymis that are selected and sampled using high-power optical magnification provided by an operating microscope. Retrieved sperm are subsequently used for intracytoplasmic sperm injection (ICSI) to induce fertilization and pregnancy. MESA is considered by many experts to be the gold standard technique for sperm retrieval in men with obstructive azoospermia given its high yield of quality sperm, excellent reported fertilization and pregnancy rates, and low risk of complications. However, MESA must be performed in an operating room, requires microsurgical skills and is only useful for reproduction using ICSI. Herein we present an overview of the evaluation of candidate patients for MESA, the technical performance of the procedure and the outcomes that have been reported.

Original languageEnglish (US)
Pages (from-to)40-43
Number of pages4
JournalAsian Journal of Andrology
Issue number1
StatePublished - Jan 2013
Externally publishedYes


  • ICSI
  • MESA
  • azoospermia
  • infertility
  • male
  • microsurgery
  • microsurgical epididymal sperm aspiration
  • sperm retrieval

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Microsurgical epididymal sperm aspiration: Indications, techniques and outcomes'. Together they form a unique fingerprint.

Cite this