Microdose gentamicin delivered via the round window microcatheter: A therapeutic option in Menière's disease

Peter Weisskopf, Michael E. Hoffer, Richard D. Kopke, Kim Gottshall, Keith Allen, Derin Wester

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Transtympanic gentamicin therapy is becoming an increasingly popular treatment for Menière's disease. Despite its popularity, transtympanic therapy is not without controversy. Vertigo cure rates are high, but hearing loss rates are variable. The best total dose of medicine, the best route of administration, and the best end-point of therapy have not been established. Meanwhile, the mode of action of gentamicin in controlling Menière's disease is still not completely understood. In the last several years, many groups have started to use a variety of sustained release devices to more accurately control the amount of gentamicin administered to the ear. This report discusses the use of one such sustained release device, and the effects of its use with very low doses of gentamicin, on the symptoms of Menière's disease.

Original languageEnglish (US)
Pages (from-to)154-156
Number of pages3
JournalOperative Techniques in Otolaryngology - Head and Neck Surgery
Volume12
Issue number3
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Fingerprint Dive into the research topics of 'Microdose gentamicin delivered via the round window microcatheter: A therapeutic option in Menière's disease'. Together they form a unique fingerprint.

  • Cite this