Microdialysis in the Neurocritical Care Unit

Ryan Kitagawa, Shoji Yokobori, Anna T. Mazzeo, Ross Bullock

Research output: Contribution to journalReview article

12 Scopus citations


Effective monitoring is critical for neurologically compromised patients, and several techniques are available. One of these tools, cerebral microdialysis (MD), was designed to detect derangements in cerebral metabolism. Although this monitoring device began as a research instrument, favorable results and utility have broadened its clinical applications. Combined with other brain monitoring techniques, MD can be used to estimate cerebral vulnerability, to assess tissue outcome, and possibly to prevent secondary ischemic injury by guiding therapy. This article reviews the literature regarding the past, present, and future uses of MD along with its advantages and disadvantages in the intensive care unit setting.

Original languageEnglish (US)
Pages (from-to)417-426
Number of pages10
JournalNeurosurgery clinics of North America
Issue number3
StatePublished - Jul 1 2013


  • Microdialysis
  • Neuromonitoring
  • Subarachnoid hemorrhage
  • Traumatic brain injury

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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    Kitagawa, R., Yokobori, S., Mazzeo, A. T., & Bullock, R. (2013). Microdialysis in the Neurocritical Care Unit. Neurosurgery clinics of North America, 24(3), 417-426. https://doi.org/10.1016/j.nec.2013.02.002