Microcantilever biosensors

R. Datar, A. Passian, R. Desikan, T. Thundat

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Microcantilever arrays have been used for multiplexed, label-free detection of biomolecules. Adsorption of analyte molecules on immobilized receptors on the cantilevers result in cantilever bending due to surface free energy variation. Piezoresistive readout of cantilever bending offers a simple method of signal transduction that is compatible with microfabrication. Although the microcantilever-based biosensing appears to high sensitivity and selectivity, reproducibility of the technique appears to be a challenge. We have developed a novel method of immobilizing receptors that increases the reproducibility. We have demonstrated simultaneous detection of cancer and cardiac markers using cantilever arrays with immobilized receptors.

Original languageEnglish (US)
Title of host publicationThe 6th IEEE Conference on SENSORS, IEEE SENSORS 2007
Number of pages1
DOIs
StatePublished - Dec 1 2007
Event6th IEEE Conference on SENSORS, IEEE SENSORS 2007 - Atlanta, GA, United States
Duration: Oct 28 2007Oct 31 2007

Publication series

NameProceedings of IEEE Sensors

Other

Other6th IEEE Conference on SENSORS, IEEE SENSORS 2007
CountryUnited States
CityAtlanta, GA
Period10/28/0710/31/07

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ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

Datar, R., Passian, A., Desikan, R., & Thundat, T. (2007). Microcantilever biosensors. In The 6th IEEE Conference on SENSORS, IEEE SENSORS 2007 [4388320] (Proceedings of IEEE Sensors). https://doi.org/10.1109/ICSENS.2007.4388320