Abstract
The authors studied methionine and creatine metabolism in females with Rett syndrome. Plasma metabolites (including methionine, homocysteine, guanidinoacetate) and urine creatine/creatinine ratios in 29 females with Rett syndrome were within the age-appropriate range. Although the authors have not been able to identify any abnormalities, it can be speculated that patients with Rett syndrome may benefit from dietary intervention to increase the supply of labile methyl groups to affected tissues.
| Original language | English |
|---|---|
| Pages (from-to) | 635-638 |
| Number of pages | 4 |
| Journal | Journal of Child Neurology |
| Volume | 22 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 1 2007 |
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Keywords
- Homocysteine
- Methionine
- Methylation
- Rett syndrome
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
Cite this
Methylation status in females with Rett syndrome. / Freilinger, Michael; Kalisch, David; Müehl, Adolf; Haas, Oskar; Moritz, Anne; Bodamer, Olaf.
In: Journal of Child Neurology, Vol. 22, No. 5, 01.05.2007, p. 635-638.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Methylation status in females with Rett syndrome
AU - Freilinger, Michael
AU - Kalisch, David
AU - Müehl, Adolf
AU - Haas, Oskar
AU - Moritz, Anne
AU - Bodamer, Olaf
PY - 2007/5/1
Y1 - 2007/5/1
N2 - The authors studied methionine and creatine metabolism in females with Rett syndrome. Plasma metabolites (including methionine, homocysteine, guanidinoacetate) and urine creatine/creatinine ratios in 29 females with Rett syndrome were within the age-appropriate range. Although the authors have not been able to identify any abnormalities, it can be speculated that patients with Rett syndrome may benefit from dietary intervention to increase the supply of labile methyl groups to affected tissues.
AB - The authors studied methionine and creatine metabolism in females with Rett syndrome. Plasma metabolites (including methionine, homocysteine, guanidinoacetate) and urine creatine/creatinine ratios in 29 females with Rett syndrome were within the age-appropriate range. Although the authors have not been able to identify any abnormalities, it can be speculated that patients with Rett syndrome may benefit from dietary intervention to increase the supply of labile methyl groups to affected tissues.
KW - Homocysteine
KW - Methionine
KW - Methylation
KW - Rett syndrome
UR - http://www.scopus.com/inward/record.url?scp=34250782723&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34250782723&partnerID=8YFLogxK
U2 - 10.1177/0883073807302616
DO - 10.1177/0883073807302616
M3 - Article
C2 - 17690074
AN - SCOPUS:34250782723
VL - 22
SP - 635
EP - 638
JO - Journal of Child Neurology
JF - Journal of Child Neurology
SN - 0883-0738
IS - 5
ER -