Method to perform IV injections on mice using the facial vein

Howard Levene, M. Zhang, C. J. Erb, J. I. Jallo, C. M. Loftus, R. F. Tuma

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.

Original languageEnglish
Pages (from-to)304-307
Number of pages4
JournalJournal of Neuroscience Methods
Volume164
Issue number2
DOIs
StatePublished - Aug 30 2007
Externally publishedYes

Fingerprint

Veins
Lacrimal Apparatus
Injections
Biomechanical Phenomena
Needles

Keywords

  • Facial vein
  • Intravenous injection
  • Murine
  • Spinal cord injury

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Method to perform IV injections on mice using the facial vein. / Levene, Howard; Zhang, M.; Erb, C. J.; Jallo, J. I.; Loftus, C. M.; Tuma, R. F.

In: Journal of Neuroscience Methods, Vol. 164, No. 2, 30.08.2007, p. 304-307.

Research output: Contribution to journalArticle

Levene, Howard ; Zhang, M. ; Erb, C. J. ; Jallo, J. I. ; Loftus, C. M. ; Tuma, R. F. / Method to perform IV injections on mice using the facial vein. In: Journal of Neuroscience Methods. 2007 ; Vol. 164, No. 2. pp. 304-307.
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