Method to perform IV injections on mice using the facial vein

Howard Levene, M. Zhang, C. J. Erb, J. I. Jallo, C. M. Loftus, R. F. Tuma

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.

Original languageEnglish
Pages (from-to)304-307
Number of pages4
JournalJournal of Neuroscience Methods
Volume164
Issue number2
DOIs
StatePublished - Aug 30 2007
Externally publishedYes

Fingerprint

Veins
Lacrimal Apparatus
Injections
Biomechanical Phenomena
Needles

Keywords

  • Facial vein
  • Intravenous injection
  • Murine
  • Spinal cord injury

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Levene, H., Zhang, M., Erb, C. J., Jallo, J. I., Loftus, C. M., & Tuma, R. F. (2007). Method to perform IV injections on mice using the facial vein. Journal of Neuroscience Methods, 164(2), 304-307. https://doi.org/10.1016/j.jneumeth.2007.05.007

Method to perform IV injections on mice using the facial vein. / Levene, Howard; Zhang, M.; Erb, C. J.; Jallo, J. I.; Loftus, C. M.; Tuma, R. F.

In: Journal of Neuroscience Methods, Vol. 164, No. 2, 30.08.2007, p. 304-307.

Research output: Contribution to journal › Article

Levene, H, Zhang, M, Erb, CJ, Jallo, JI, Loftus, CM & Tuma, RF 2007, 'Method to perform IV injections on mice using the facial vein', Journal of Neuroscience Methods, vol. 164, no. 2, pp. 304-307. https://doi.org/10.1016/j.jneumeth.2007.05.007
Levene H, Zhang M, Erb CJ, Jallo JI, Loftus CM, Tuma RF. Method to perform IV injections on mice using the facial vein. Journal of Neuroscience Methods. 2007 Aug 30;164(2):304-307. https://doi.org/10.1016/j.jneumeth.2007.05.007
Levene, Howard ; Zhang, M. ; Erb, C. J. ; Jallo, J. I. ; Loftus, C. M. ; Tuma, R. F. / Method to perform IV injections on mice using the facial vein. In: Journal of Neuroscience Methods. 2007 ; Vol. 164, No. 2. pp. 304-307.
@article{0f1453d707cd407ab6579992ea16e46a,
title = "Method to perform IV injections on mice using the facial vein",
abstract = "A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93{\%}) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.",
keywords = "Facial vein, Intravenous injection, Murine, Spinal cord injury",
author = "Howard Levene and M. Zhang and Erb, {C. J.} and Jallo, {J. I.} and Loftus, {C. M.} and Tuma, {R. F.}",
year = "2007",
month = "8",
day = "30",
doi = "10.1016/j.jneumeth.2007.05.007",
language = "English",
volume = "164",
pages = "304--307",
journal = "Journal of Neuroscience Methods",
issn = "0165-0270",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Method to perform IV injections on mice using the facial vein

AU - Levene, Howard

AU - Zhang, M.

AU - Erb, C. J.

AU - Jallo, J. I.

AU - Loftus, C. M.

AU - Tuma, R. F.

PY - 2007/8/30

Y1 - 2007/8/30

N2 - A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.

AB - A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.

KW - Facial vein

KW - Intravenous injection

KW - Murine

KW - Spinal cord injury

UR - http://www.scopus.com/inward/record.url?scp=34347323941&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34347323941&partnerID=8YFLogxK

U2 - 10.1016/j.jneumeth.2007.05.007

DO - 10.1016/j.jneumeth.2007.05.007

M3 - Article

C2 - 17574682

AN - SCOPUS:34347323941

VL - 164

SP - 304

EP - 307

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

IS - 2

ER -

Access to Document