Method to perform IV injections on mice using the facial vein

H. B. Levene; M. Zhang; C. J. Erb; J. I. Jallo; C. M. Loftus; R. F. Tuma

doi:10.1016/j.jneumeth.2007.05.007

Method to perform IV injections on mice using the facial vein

H. B. Levene, M. Zhang, C. J. Erb, J. I. Jallo, C. M. Loftus, R. F. Tuma

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

A novel technique for gaining IV access in a mouse model is presented. Using a cut-down approach, the facial vein is identified through an incision from anterior to the external auditory meatus to posterior to the lateral ispilateral canthus. A small gage needle (30 gauge) may be inserted to inject medications. A high success rate (93%) as determined by direct visualization is achieved. The technique would prove especially useful for animals slated for kinematic testing as the incision does not interfere with the animal's ventral surface.

Original language	English (US)
Pages (from-to)	304-307
Number of pages	4
Journal	Journal of Neuroscience Methods
Volume	164
Issue number	2
DOIs	https://doi.org/10.1016/j.jneumeth.2007.05.007
State	Published - Aug 30 2007
Externally published	Yes

Keywords

Facial vein
Intravenous injection
Murine
Spinal cord injury

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1016/j.jneumeth.2007.05.007

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Cite this

Levene, H. B., Zhang, M., Erb, C. J., Jallo, J. I., Loftus, C. M., & Tuma, R. F. (2007). Method to perform IV injections on mice using the facial vein. Journal of Neuroscience Methods, 164(2), 304-307. https://doi.org/10.1016/j.jneumeth.2007.05.007

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AU - Zhang, M.

AU - Erb, C. J.

AU - Jallo, J. I.

AU - Loftus, C. M.

AU - Tuma, R. F.

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KW - Intravenous injection

KW - Murine

KW - Spinal cord injury

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