Abstract
Intra-arterial infusion of methionine-enkaphalin or morphine caused a dose-dependent increase in histamine-induced gastric secretion and gastric mucosal blood flow. Administration of naloxone resulted in the reduction of both gastric secretion and mucosal circulation indicating that oxyntic cells possess specific opiate receptors and that opiate peptides may be involved in the stimulation of gastric secretion.
| Original language | English |
|---|---|
| Pages (from-to) | 156-160 |
| Number of pages | 5 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 158 |
| Issue number | 2 |
| State | Published - Dec 1 1978 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Methionine-enkephalin stimulates gastric secretion and gastric mucosal blood flow. / Konturek, S. J.; Pawlik, W.; Walus, K. M.; Coy, D. H.; Schally, Andrew V.
In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 158, No. 2, 01.12.1978, p. 156-160.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Methionine-enkephalin stimulates gastric secretion and gastric mucosal blood flow
AU - Konturek, S. J.
AU - Pawlik, W.
AU - Walus, K. M.
AU - Coy, D. H.
AU - Schally, Andrew V
PY - 1978/12/1
Y1 - 1978/12/1
N2 - Intra-arterial infusion of methionine-enkaphalin or morphine caused a dose-dependent increase in histamine-induced gastric secretion and gastric mucosal blood flow. Administration of naloxone resulted in the reduction of both gastric secretion and mucosal circulation indicating that oxyntic cells possess specific opiate receptors and that opiate peptides may be involved in the stimulation of gastric secretion.
AB - Intra-arterial infusion of methionine-enkaphalin or morphine caused a dose-dependent increase in histamine-induced gastric secretion and gastric mucosal blood flow. Administration of naloxone resulted in the reduction of both gastric secretion and mucosal circulation indicating that oxyntic cells possess specific opiate receptors and that opiate peptides may be involved in the stimulation of gastric secretion.
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UR - http://www.scopus.com/inward/citedby.url?scp=0018149777&partnerID=8YFLogxK
M3 - Article
C2 - 209471
AN - SCOPUS:0018149777
VL - 158
SP - 156
EP - 160
JO - Experimental Biology and Medicine
JF - Experimental Biology and Medicine
SN - 0037-9727
IS - 2
ER -