Methicillin-resistant Staphylococcus epidermidis isolation from the vitrectomy specimen four hours after initial treatment with vancomycin and ceftazidime

Golnaz Javey, Stephen G. Schwartz, Andrew A. Moshfeghi, Sanjay Asrani, Harry W. Flynn

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A patient presented with acute-onset, postoperative endophthalmitis and visual acuity of light perception. Because of a time delay in arranging a pars plana vitrectomy (PPV), the patient was treated with a prompt vitreous tap for culture an injection of vancomycin and ceftazidime. Four hours later, the PPV was performed and additional antibiotics were injected. The cultures from both the initial needle tap and the subsequent PPV isolated methicillinresistant Staphylococcus epidermidis sensitive to vancomycin, but resistant to fourth-generation fluoroquinolones. The patient eventually recovered a visual acuity of 20/80 before developing retinal detachment. This case illustrates the time lag necessary to sterilize the vitreous cavity, and suggests a possible two-step staged treatment strategy for situations in which access to PPV equipment and support staff may be limited.

Original languageEnglish (US)
Pages (from-to)101-104
Number of pages4
JournalClinical Ophthalmology
Volume4
Issue number1
StatePublished - Apr 30 2010

Keywords

  • Endophthalmitis
  • Pars plana vitrectomy
  • Tap and inject

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Methicillin-resistant Staphylococcus epidermidis isolation from the vitrectomy specimen four hours after initial treatment with vancomycin and ceftazidime'. Together they form a unique fingerprint.

Cite this