Metastatic disease to the cavernous sinus: Clinical syndrome and ct diagnosis

M. Judith Donovan Post, Danae R. Mendez, Lanning B. Kline, James D. Acker, Joel S. Glaser

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


We analyzed the clinical constellation of signs and symptoms and the radiographic studies of 17 patients with histologic verification of cavernous sinus metastases. Although most patients presented with acute, unilateral, painful ophthalmoplegia, and with a rapidly progressive course, the clinical diagnosis of metastatic disease was often delayed. This was probably due to the fact that, in the majority of patients, cavernous sinus symptoms were either the first expression of an unknown malignancy or the first manifestation of metastatic disease in those with a known primary. Computed tomography was found to be an indispensable diagnostic aid. In 16 of the 17 patients CT established the presence of an enhancing mass in the cavernous sinus sometimes associated with bone erosion. Thin section, contrast enhanced high resolution CT in axial and coronal projections represents in the imaging procedure of choice for metastatic disease to the cavernous sinus.

Original languageEnglish (US)
Pages (from-to)115-120
Number of pages6
JournalJournal of computer assisted tomography
Issue number1
StatePublished - Jan 1 1985


  • Carcinoma
  • Cavernous sinus
  • Computed tomography
  • Metastatic
  • Ophthalmoplegia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Metastatic disease to the cavernous sinus: Clinical syndrome and ct diagnosis'. Together they form a unique fingerprint.

Cite this