Chronic kidney disease (CKD) is associated with a high risk of death. Dyslipidemia is commonly observed in patients with CKD and is accompanied by a decrease in plasma high-density lipoprotein (HDL), and an increase in plasma triglyceride-rich lipoproteins and oxidized lipids. The observation that statins may decrease albuminuria but do not stop the progression of CKD indicates that pathways other than the cholesterol synthesis contribute to cholesterol accumulation in the kidneys of patients with CKD.
- Glomerular disease
- Kidney disease
- Renal disease
- Reverse cholesterol transport
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism