Mesenchymal stem cells in the induction of transplantation tolerance.

Amelia Bartholomew, David Polchert, Erzsebet Szilagyi, G. W. Douglas, Norma Kenyon

Research output: Contribution to journalReview article

19 Scopus citations

Abstract

Mesenchymal stem cells directly suppress ongoing immune responses. Through production of toleragenic cytokines, inhibition of lymphocyte proliferation, delivery of reparative and protective signals after reperfusion injury, and facilitation of hematopoietic chimerism, these cells demonstrate a wide-ranging potential for the development of multifaceted toleragenic strategies after transplantation.

Original languageEnglish (US)
Pages (from-to)S55-57
JournalTransplantation
Volume87
Issue number9 Suppl
StatePublished - May 15 2009
Externally publishedYes

ASJC Scopus subject areas

  • Transplantation

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  • Cite this

    Bartholomew, A., Polchert, D., Szilagyi, E., Douglas, G. W., & Kenyon, N. (2009). Mesenchymal stem cells in the induction of transplantation tolerance. Transplantation, 87(9 Suppl), S55-57.