TY - JOUR
T1 - Mesenchymal Stem Cells
T2 - Emerging Therapy for Duchenne Muscular Dystrophy
AU - Markert, Chad D.
AU - Atala, Anthony
AU - Cann, Jennifer K.
AU - Christ, George
AU - Furth, Mark
AU - Ambrosio, Fabrisia
AU - Childers, Martin K.
PY - 2009/6
Y1 - 2009/6
N2 - Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the bone marrow, distinct from blood-forming stem cells. Based on the embryologic derivation, availability, and various pro-regenerative characteristics, research exploring their use in cell therapy shows great promise for patients with degenerative muscle diseases and a number of other conditions. In this review, the authors explore the potential for mesenchymal stem cell therapy in the emerging field of regenerative medicine with a focus on treatment for Duchenne muscular dystrophy.
AB - Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the bone marrow, distinct from blood-forming stem cells. Based on the embryologic derivation, availability, and various pro-regenerative characteristics, research exploring their use in cell therapy shows great promise for patients with degenerative muscle diseases and a number of other conditions. In this review, the authors explore the potential for mesenchymal stem cell therapy in the emerging field of regenerative medicine with a focus on treatment for Duchenne muscular dystrophy.
UR - http://www.scopus.com/inward/record.url?scp=67249147702&partnerID=8YFLogxK
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U2 - 10.1016/j.pmrj.2009.02.013
DO - 10.1016/j.pmrj.2009.02.013
M3 - Review article
C2 - 19627945
AN - SCOPUS:67249147702
VL - 1
SP - 547
EP - 559
JO - PM and R
JF - PM and R
SN - 1934-1482
IS - 6
ER -