Mesenchymal Stem Cells: Emerging Therapy for Duchenne Muscular Dystrophy

Chad D. Markert, Anthony Atala, Jennifer K. Cann, George Christ, Mark Furth, Fabrisia Ambrosio, Martin K. Childers

Research output: Contribution to journalReview article

32 Scopus citations

Abstract

Multipotent cells that can give rise to bone, cartilage, fat, connective tissue, and skeletal and cardiac muscle are termed mesenchymal stem cells. These cells were first identified in the bone marrow, distinct from blood-forming stem cells. Based on the embryologic derivation, availability, and various pro-regenerative characteristics, research exploring their use in cell therapy shows great promise for patients with degenerative muscle diseases and a number of other conditions. In this review, the authors explore the potential for mesenchymal stem cell therapy in the emerging field of regenerative medicine with a focus on treatment for Duchenne muscular dystrophy.

Original languageEnglish (US)
Pages (from-to)547-559
Number of pages13
JournalPM and R
Volume1
Issue number6
DOIs
StatePublished - Jun 2009

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Mesenchymal Stem Cells: Emerging Therapy for Duchenne Muscular Dystrophy'. Together they form a unique fingerprint.

  • Cite this

    Markert, C. D., Atala, A., Cann, J. K., Christ, G., Furth, M., Ambrosio, F., & Childers, M. K. (2009). Mesenchymal Stem Cells: Emerging Therapy for Duchenne Muscular Dystrophy. PM and R, 1(6), 547-559. https://doi.org/10.1016/j.pmrj.2009.02.013