Meningioangiomatosis: Clinical, radiologic, and histopathologic correlation

Richard N. Aizpuru, Robert Quencer, Michael D Norenberg, Nolan Altman, James Smirniotopoulos

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Meningioangiomatosis (MA) is a rare, benign, hamartomatous lesion of the leptomeninges; MA has been considered to be a forme fruste of neurofibromatosis. A review of pathology records for patients with MA who were seen between 1970 and 1989 at the authors' institutions revealed four patients (three male and one female; aged 2.5-21.0 years; mean, 10.8 years) with a history of seizures but without the stigmata or family history of neurofibromatosis. Three patients had undergone either computed tomographic (CT) or magnetic resonance (MR) imaging studies. All patients had undergone craniotomies to obtain tissue for pathologic analysis; a peripheral, leptomeningeal lesion was found in all four patients. At CT in two patients, the lesions were most consistent with calcification. At T2-weighted MR imaging in one patient, the lesion demonstrated a hyperintense periphery with associated edema of the white matter. Histopathologic examination demonstrated characteristic features of MA - cortical meningovascular fibroblastic proliferation and leptomeningeal calcification. The accurate diagnosis of MA is important since MA is a benign, surgically correctable cause of seizures.

Original languageEnglish
Pages (from-to)819-821
Number of pages3
JournalRadiology
Volume179
Issue number3
StatePublished - Jun 1 1991

Fingerprint

Neurofibromatoses
Seizures
Magnetic Resonance Imaging
Christianity
Craniotomy
Edema
Pathology
White Matter

Keywords

  • Brain neoplasms, CT, 13.1211
  • Brain neoplasms, diagnosis, 13.366
  • Brain neoplasms, MR studies, 13.1214
  • Brain, calcification
  • Meninges, CT, 139.211
  • Meninges, MR studies, 139.1214
  • Meninges, neoplasms, 139.366
  • Meningioangiomatosis, 139.366

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Aizpuru, R. N., Quencer, R., Norenberg, M. D., Altman, N., & Smirniotopoulos, J. (1991). Meningioangiomatosis: Clinical, radiologic, and histopathologic correlation. Radiology, 179(3), 819-821.

Meningioangiomatosis : Clinical, radiologic, and histopathologic correlation. / Aizpuru, Richard N.; Quencer, Robert; Norenberg, Michael D; Altman, Nolan; Smirniotopoulos, James.

In: Radiology, Vol. 179, No. 3, 01.06.1991, p. 819-821.

Research output: Contribution to journalArticle

Aizpuru, RN, Quencer, R, Norenberg, MD, Altman, N & Smirniotopoulos, J 1991, 'Meningioangiomatosis: Clinical, radiologic, and histopathologic correlation', Radiology, vol. 179, no. 3, pp. 819-821.
Aizpuru, Richard N. ; Quencer, Robert ; Norenberg, Michael D ; Altman, Nolan ; Smirniotopoulos, James. / Meningioangiomatosis : Clinical, radiologic, and histopathologic correlation. In: Radiology. 1991 ; Vol. 179, No. 3. pp. 819-821.
@article{aa52806633014ab386ca75321224d1db,
title = "Meningioangiomatosis: Clinical, radiologic, and histopathologic correlation",
abstract = "Meningioangiomatosis (MA) is a rare, benign, hamartomatous lesion of the leptomeninges; MA has been considered to be a forme fruste of neurofibromatosis. A review of pathology records for patients with MA who were seen between 1970 and 1989 at the authors' institutions revealed four patients (three male and one female; aged 2.5-21.0 years; mean, 10.8 years) with a history of seizures but without the stigmata or family history of neurofibromatosis. Three patients had undergone either computed tomographic (CT) or magnetic resonance (MR) imaging studies. All patients had undergone craniotomies to obtain tissue for pathologic analysis; a peripheral, leptomeningeal lesion was found in all four patients. At CT in two patients, the lesions were most consistent with calcification. At T2-weighted MR imaging in one patient, the lesion demonstrated a hyperintense periphery with associated edema of the white matter. Histopathologic examination demonstrated characteristic features of MA - cortical meningovascular fibroblastic proliferation and leptomeningeal calcification. The accurate diagnosis of MA is important since MA is a benign, surgically correctable cause of seizures.",
keywords = "Brain neoplasms, CT, 13.1211, Brain neoplasms, diagnosis, 13.366, Brain neoplasms, MR studies, 13.1214, Brain, calcification, Meninges, CT, 139.211, Meninges, MR studies, 139.1214, Meninges, neoplasms, 139.366, Meningioangiomatosis, 139.366",
author = "Aizpuru, {Richard N.} and Robert Quencer and Norenberg, {Michael D} and Nolan Altman and James Smirniotopoulos",
year = "1991",
month = "6",
day = "1",
language = "English",
volume = "179",
pages = "819--821",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "3",

}

TY - JOUR

T1 - Meningioangiomatosis

T2 - Clinical, radiologic, and histopathologic correlation

AU - Aizpuru, Richard N.

AU - Quencer, Robert

AU - Norenberg, Michael D

AU - Altman, Nolan

AU - Smirniotopoulos, James

PY - 1991/6/1

Y1 - 1991/6/1

N2 - Meningioangiomatosis (MA) is a rare, benign, hamartomatous lesion of the leptomeninges; MA has been considered to be a forme fruste of neurofibromatosis. A review of pathology records for patients with MA who were seen between 1970 and 1989 at the authors' institutions revealed four patients (three male and one female; aged 2.5-21.0 years; mean, 10.8 years) with a history of seizures but without the stigmata or family history of neurofibromatosis. Three patients had undergone either computed tomographic (CT) or magnetic resonance (MR) imaging studies. All patients had undergone craniotomies to obtain tissue for pathologic analysis; a peripheral, leptomeningeal lesion was found in all four patients. At CT in two patients, the lesions were most consistent with calcification. At T2-weighted MR imaging in one patient, the lesion demonstrated a hyperintense periphery with associated edema of the white matter. Histopathologic examination demonstrated characteristic features of MA - cortical meningovascular fibroblastic proliferation and leptomeningeal calcification. The accurate diagnosis of MA is important since MA is a benign, surgically correctable cause of seizures.

AB - Meningioangiomatosis (MA) is a rare, benign, hamartomatous lesion of the leptomeninges; MA has been considered to be a forme fruste of neurofibromatosis. A review of pathology records for patients with MA who were seen between 1970 and 1989 at the authors' institutions revealed four patients (three male and one female; aged 2.5-21.0 years; mean, 10.8 years) with a history of seizures but without the stigmata or family history of neurofibromatosis. Three patients had undergone either computed tomographic (CT) or magnetic resonance (MR) imaging studies. All patients had undergone craniotomies to obtain tissue for pathologic analysis; a peripheral, leptomeningeal lesion was found in all four patients. At CT in two patients, the lesions were most consistent with calcification. At T2-weighted MR imaging in one patient, the lesion demonstrated a hyperintense periphery with associated edema of the white matter. Histopathologic examination demonstrated characteristic features of MA - cortical meningovascular fibroblastic proliferation and leptomeningeal calcification. The accurate diagnosis of MA is important since MA is a benign, surgically correctable cause of seizures.

KW - Brain neoplasms, CT, 13.1211

KW - Brain neoplasms, diagnosis, 13.366

KW - Brain neoplasms, MR studies, 13.1214

KW - Brain, calcification

KW - Meninges, CT, 139.211

KW - Meninges, MR studies, 139.1214

KW - Meninges, neoplasms, 139.366

KW - Meningioangiomatosis, 139.366

UR - http://www.scopus.com/inward/record.url?scp=0025806259&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025806259&partnerID=8YFLogxK

M3 - Article

C2 - 2027998

AN - SCOPUS:0025806259

VL - 179

SP - 819

EP - 821

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 3

ER -