Medical management of children after liver transplantation

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Purpose of review: Successful outcomes in patient, graft survival, and quality of life depend on the prevention, early detection, and treatment of possible complications. The aim of the study was to highlight the common outcomes focusing on the unique features in children. Medical follow-up of children after liver transplantation includes monitoring of surgical complications: biliary and vascular, rejection, infections, posttransplant lymphoproliferative disease, other malignancies, recurrent disease, graft function, hypertension, diabetes, renal failure, among other conditions. The goal is to maintain normal graft function on minimal immunosuppression to avoid medication-induced side-effects. Recent findings: Recent findings include the importance of meticulous follow-up of Epstein-Barr virus and Cytomegalic virus viral load, leading to early diagnosis and improved prognosis, increased prevalence of renal toxicity, cognitive dysfunction, autoimmune, atopic and eosinophilic disease, oral hygiene and chronic hepatitis, and fibrosis of allografts. Summary: Caring for children after liver transplantation is extremely rewarding; however, careful attention must be paid to a variety of systems with understanding of the distinctiveness of pediatrics to assure optimal outcomes.

Original languageEnglish (US)
Pages (from-to)474-479
Number of pages6
JournalCurrent Opinion in Organ Transplantation
Volume19
Issue number5
DOIs
StatePublished - Oct 1 2014
Externally publishedYes

Keywords

  • Children
  • Liver transplantation
  • Medical management
  • Pediatric

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation

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