Mediation of responses to calcium in taste cells by modulation of a potassium conductance

Albertino R. Bigiani, Stephen D. Roper

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Calcium salts are strong taste stimuli in vertebrate animals. However, the chemosensory transduction mechanisms for calcium are not known. In taste buds of Necturus maculosus (mud puppy), calcium evokes depolarizing receptor potentials by acting extracellularly on the apical ends of taste cells to block a resting potassium conductance. Therefore, divalent cations elicit receptor potentials in taste cells by modulating a potassium conductance rather than by permeating the cell membrane, the mechanism utilized by monovalent cations such as sodium and potassium ions.

Original languageEnglish (US)
Pages (from-to)126-128
Number of pages3
JournalScience
Volume252
Issue number5002
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

ASJC Scopus subject areas

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