Mediastinoscopy. A diagnostic aid in metastatic carcinoma of the breast

James P. Neifeld, James N. Ingle, Douglass C. Tormey, Marc E. Lippman, Steven D. Richman, Lawrence L. Michaelis

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Six patients with metastatic carcinoma of the breast underwent mediastinoscopy to obtain tissue for estrogen receptor analysis and pathologic confirmation of metastatic tumor. The indication for mediastinoscopy was an abnormal mediastinal accumulation of gallium in five patients, only two of whom had an abnormality noted on tomography. All six patients had tumor recovered by mediastinoscopy as demonstrated by pathologic examination and/or estrogen receptor assay. Therefore, the diagnosis of mediastinal metastases in breast cancer may be suggested by either chest roentgenograms, mediastinal tomography, or gallium scintigraphy. Mediastinoscopy is a safe, effective procedure capable of establishing the diagnosis of metastatic carcinoma of the breast and of procuring sufficient tissue for estrogen receptor analysis in patients without more readily accessible sites of metastases.

Original languageEnglish (US)
Pages (from-to)1973-1976
Number of pages4
JournalCancer
Volume37
Issue number4
DOIs
StatePublished - Apr 1976

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Neifeld, J. P., Ingle, J. N., Tormey, D. C., Lippman, M. E., Richman, S. D., & Michaelis, L. L. (1976). Mediastinoscopy. A diagnostic aid in metastatic carcinoma of the breast. Cancer, 37(4), 1973-1976. https://doi.org/10.1002/1097-0142(197604)37:4<1973::AID-CNCR2820370449>3.0.CO;2-R