Medial preoptic connections with the midbrain tegmentum are essential for male sexual behavior

Nancy L. Brackett, David A. Edwards

Research output: Contribution to journalArticle

80 Scopus citations

Abstract

The medial preoptic area appears to play a major role in the control of sexual behavior. Efferents from the medial preoptic area course through the medial forebrain bundle to pass through and/or terminate in the dorsolateral and ventral tegmentum of the midbrain. Bilateral lesions of the dorsolateral tegmentum eliminate mating behavior in male rats, reproducing the effect of bilateral medial preoptic lesions. Sexual behavior is also eliminated when a preoptic lesion on one side of the brain is combined with a lesion of the dorsolateral tegmentum on the other side of the brain. In other words, asymmetric brain damage which bilaterally destroys the preoptic connections with the dorsolateral tegmentum eliminates male sexual behavior, and we conclude that the connections between these two regions are essential for copulation.

Original languageEnglish (US)
Pages (from-to)79-84
Number of pages6
JournalPhysiology AND Behavior
Volume32
Issue number1
DOIs
StatePublished - Jan 1984
Externally publishedYes

Keywords

  • Brain lesions
  • Male sex behavior
  • Medial preoptic area
  • Midbrain tegmentum

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

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