Mechanical treatment of vasospasm

Raqeeb Haque, Christopher P. Kellner, Ricardo J Komotar, E. Sander Connolly, Sean D. Lavine, Robert A. Solomon, Philip M. Meyers

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: Since cerebral vasospasm (CV) was first described nearly half a century ago, significant progress has been made in understanding its underlying pathophysiology and developing treatment modalities. The purpose of this review is to discuss the rationale behind mechanical interventions for CV as well as the efficacy and complications associated with these treatment options. Methods: The authors summarize the pertinent literature on the mechanical treatment of CV, focusing first on balloon angioplasty, second on therapy combined with intra-arterial drug infusion, and concluding by briefly discussing intra-aortic balloon counterpulsation. The epidemiology, pathophysiology, technique, outcome, timing and complications are discussed for each treatment option. Results: A review of the relevant medical literature reveals that in the last 20 years, endovascular techniques including transluminal balloon angioplasty, intra-arterial drug infusion and newer experimental strategies have provided an important supplement to the established medical therapy. Discussion: Despite these developments, however, CV remains a major contributor to poor outcome following aSAH and continued efforts are necessary to improve and refine endovascular strategies as well as develop new treatment modalities.

Original languageEnglish
Pages (from-to)638-643
Number of pages6
JournalNeurological Research
Volume31
Issue number6
DOIs
StatePublished - Jul 1 2009
Externally publishedYes

Fingerprint

Intracranial Vasospasm
Intra Arterial Infusions
Balloon Angioplasty
Therapeutics
Counterpulsation
Endovascular Procedures
Angioplasty
Pharmaceutical Preparations
Epidemiology

Keywords

  • Angioplasty
  • Endovascular treatment
  • Subarachnoid hemorrhage
  • Vasospasm

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Haque, R., Kellner, C. P., Komotar, R. J., Connolly, E. S., Lavine, S. D., Solomon, R. A., & Meyers, P. M. (2009). Mechanical treatment of vasospasm. Neurological Research, 31(6), 638-643. https://doi.org/10.1179/174313209X455745

Mechanical treatment of vasospasm. / Haque, Raqeeb; Kellner, Christopher P.; Komotar, Ricardo J; Connolly, E. Sander; Lavine, Sean D.; Solomon, Robert A.; Meyers, Philip M.

In: Neurological Research, Vol. 31, No. 6, 01.07.2009, p. 638-643.

Research output: Contribution to journalArticle

Haque, R, Kellner, CP, Komotar, RJ, Connolly, ES, Lavine, SD, Solomon, RA & Meyers, PM 2009, 'Mechanical treatment of vasospasm', Neurological Research, vol. 31, no. 6, pp. 638-643. https://doi.org/10.1179/174313209X455745
Haque R, Kellner CP, Komotar RJ, Connolly ES, Lavine SD, Solomon RA et al. Mechanical treatment of vasospasm. Neurological Research. 2009 Jul 1;31(6):638-643. https://doi.org/10.1179/174313209X455745
Haque, Raqeeb ; Kellner, Christopher P. ; Komotar, Ricardo J ; Connolly, E. Sander ; Lavine, Sean D. ; Solomon, Robert A. ; Meyers, Philip M. / Mechanical treatment of vasospasm. In: Neurological Research. 2009 ; Vol. 31, No. 6. pp. 638-643.
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