Mechanical behavior of human dura mater

Suzana E. Otano, Michael S. Sacks, Theodore Malinin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Human dura mater (HDM) allografts have been used extensively as a tissue replacement biomaterial. Yet, little is known about HDM biomechanical behavior, which is partially due to HDM's complex collagen fiber architecture. We used small angle light scattering to quantify HDM collagen fiber architecture to determine optimal specimen selection sites for uniaxial mechanical testing. Our results indicated that tissue specimens aligned with the preferred collagen fiber direction were stronger, stiffer, required a greater amount of energy to break the tissue and were more extensible at the ultimate tensile strength than specimens selected perpendicular to the preferred direction. The development of this tissue selection technique will allow us to more accurately assess HDM mechanical behavior in both the natural and chemically modified state.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Place of PublicationNew York, NY, United States
Number of pages2
StatePublished - Jan 1 1995
EventProceedings of the 1995 Bioengineering Conference - Beever Creek, CO, USA
Duration: Jun 28 1995Jul 2 1995


OtherProceedings of the 1995 Bioengineering Conference
CityBeever Creek, CO, USA

ASJC Scopus subject areas

  • Engineering(all)


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