Measurement of chemical shifts and coupling constants for glutamate and glutamine

Varanavasi Govindaraju, Vladimir J. Basus, Gerald B. Matson, Andrew A. Maudsley

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Proton chemical shifts and coupling constants were obtained for glutamate and glutamine in water (D2O) at pH = 6.6. Initial chemical shift and coupling constant values obtained from experimental spectra were refined using a spectral simulation and optimization program to get a complete set of values that could not otherwise be measured directly from the experimental spectra due to strong spin-spin couplings. These values are essential for automated spectral fitting procedures that require a priori information.

Original languageEnglish (US)
Pages (from-to)1011-1013
Number of pages3
JournalMagnetic Resonance in Medicine
Volume39
Issue number6
DOIs
StatePublished - Jun 1 1998
Externally publishedYes

Keywords

  • Chemical shifts
  • Glutamate
  • Glutamine
  • J coupling

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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