Maturation of normal primate white matter: Computed tomographic correlation

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Five infant baboons were examined with computed tomography (CT) during the first year of their lives to determine the rate and degree of normal white matter maturation in frontal, occipital, and parietal areas. The increase in CT numbers with age was correlated with gross and histologic specimens. Two phases of maturation were identified: a rapid phase (first 8-12 weeks) and a gradual phase (after 12 weeks). Frontal white matter was the most immature in the immediate postnatal period but it became equal in attenuation to the other regions by 4 weeks of age. Knowledge of white matter maturation rates may be particularly useful in cases of neonatal hypoxia/ischemia where zones of periventricular hypodensity are identified. The failure of such regions to follow a normal rate of maturation may indicate damage to the white matter and have significant prognostic implications.

Original languageEnglish
Pages (from-to)365-372
Number of pages8
JournalAmerican Journal of Neuroradiology
Volume3
Issue number4
StatePublished - Dec 1 1982

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Primates
Tomography
Papio
Ischemia
White Matter

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Maturation of normal primate white matter : Computed tomographic correlation. / Quencer, Robert.

In: American Journal of Neuroradiology, Vol. 3, No. 4, 01.12.1982, p. 365-372.

Research output: Contribution to journalArticle

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