Our previous studies in rats with vitamin D deficiency accompanied by hypocalcemia showed a decrease in the rates of periosteal matrix formation and osteoid maturation compared to control values. We report here that a dietary correction of the hypocalcemia also corrects the defects in matrix formation and osteoid maturation in vitamin D-deficient animals. These results suggest that the level of serum calcium plays a regulatory role in determining the rates of both bone matrix formation and maturation in rats.
|Original language||English (US)|
|Number of pages||7|
|Journal||Mineral and Electrolyte Metabolism|
|State||Published - Jan 1 1980|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism