Matrix formation and osteoid maturation in vitamin D-deficient rats made normocalcemic by dietary means

G. A. Howard, D. J. Baylink

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Our previous studies in rats with vitamin D deficiency accompanied by hypocalcemia showed a decrease in the rates of periosteal matrix formation and osteoid maturation compared to control values. We report here that a dietary correction of the hypocalcemia also corrects the defects in matrix formation and osteoid maturation in vitamin D-deficient animals. These results suggest that the level of serum calcium plays a regulatory role in determining the rates of both bone matrix formation and maturation in rats.

Original languageEnglish (US)
Pages (from-to)44-50
Number of pages7
JournalMineral and Electrolyte Metabolism
Volume3
Issue number1
StatePublished - Jan 1 1980
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry

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