Abstract
Our previous studies in rats with vitamin D deficiency accompanied by hypocalcemia showed a decrease in the rates of periosteal matrix formation and osteoid maturation compared to control values. We report here that a dietary correction of the hypocalcemia also corrects the defects in matrix formation and osteoid maturation in vitamin D-deficient animals. These results suggest that the level of serum calcium plays a regulatory role in determining the rates of both bone matrix formation and maturation in rats.
Original language | English (US) |
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Pages (from-to) | 44-50 |
Number of pages | 7 |
Journal | Mineral and Electrolyte Metabolism |
Volume | 3 |
Issue number | 1 |
State | Published - Jan 1 1980 |
Externally published | Yes |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Biochemistry