Matrix formation and osteoid maturation in vitamin D-deficient rats made normocalcemic by dietary means

G. A. Howard; D. J. Baylink

Matrix formation and osteoid maturation in vitamin D-deficient rats made normocalcemic by dietary means

Research output: Contribution to journal › Article › peer-review

Abstract

Our previous studies in rats with vitamin D deficiency accompanied by hypocalcemia showed a decrease in the rates of periosteal matrix formation and osteoid maturation compared to control values. We report here that a dietary correction of the hypocalcemia also corrects the defects in matrix formation and osteoid maturation in vitamin D-deficient animals. These results suggest that the level of serum calcium plays a regulatory role in determining the rates of both bone matrix formation and maturation in rats.

Original language	English (US)
Pages (from-to)	44-50
Number of pages	7
Journal	Mineral and Electrolyte Metabolism
Volume	3
Issue number	1
State	Published - Jan 1 1980
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Biochemistry

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abstract = "Our previous studies in rats with vitamin D deficiency accompanied by hypocalcemia showed a decrease in the rates of periosteal matrix formation and osteoid maturation compared to control values. We report here that a dietary correction of the hypocalcemia also corrects the defects in matrix formation and osteoid maturation in vitamin D-deficient animals. These results suggest that the level of serum calcium plays a regulatory role in determining the rates of both bone matrix formation and maturation in rats.",

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Matrix formation and osteoid maturation in vitamin D-deficient rats made normocalcemic by dietary means

Abstract

ASJC Scopus subject areas

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