Managing Cardiovascular Risk in the Post Solid Organ Transplant Recipient

Mrudula R. Munagala, Anita Phancao

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Solid organ transplantation is an effective treatment for patients with end-stage organ disease. The prevalence of cardiovascular diseases (CVD) has increased in recipients. CVD remains a leading cause of mortality among recipients with functioning grafts. The pathophysiology of CVD recipients is a complex interplay between preexisting risk factors, metabolic sequelae of immunosuppressive agents, infection, and rejection. Risk modification must be weighed against the risk of mortality owing to rejection or infection. Aggressive risk stratification and modification before and after transplantation and tailoring immunosuppressive regimens are essential to prevent complications and improve short-term and long-term mortality and graft survival.

Original languageEnglish (US)
Pages (from-to)519-533
Number of pages15
JournalMedical Clinics of North America
Volume100
Issue number3
DOIs
StatePublished - May 1 2016
Externally publishedYes

Keywords

  • Cardiovascular disease
  • Immunosuppression
  • Risk factors
  • Solid organ transplant
  • Survival

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint

Dive into the research topics of 'Managing Cardiovascular Risk in the Post Solid Organ Transplant Recipient'. Together they form a unique fingerprint.

Cite this