Management of pediatric airway granular cell tumor: Role of laryngotracheal reconstruction

Francisco G. Pernas, Ramzi T. Younis, David A. Lehman, Philip G. Robinson

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Objective: To discuss the role of laryngotracheal reconstruction (LTR) in granular cell tumor (GCT) and to highlight the importance and seriousness of GCT in pediatric airway cases. Methods: A historical literature review was performed and a GCT case from the University of Miami Pediatric Otolaryngology Clinic is presented to highlight the role of LTR in the treatment of GCT. Results: A case of a GCT of the laryngotracheal airway is reported and the management is discussed. Histological discussion and a review of the literature are included regarding GCT. This case is the third reported in the English literature of two synchronous GCT lesions of the upper airway repaired with a laryngotracheal reconstruction. Conclusions: In the authors' experience once conservative management consisting of endoscopic debulking has failed the treatment of choice for GCTs of the pediatric airway that are unresectable is a single stage laryngotracheal reconstruction with negative frozen section pathology to assure total wide local excision.

Original languageEnglish (US)
Pages (from-to)957-963
Number of pages7
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number6
StatePublished - Jun 1 2006


  • Airway pediatric
  • Frozen section pathology
  • Granular cell myoblastoma
  • Granular cell tumor
  • Laryngofissure approach
  • Laryngotracheal reconstruction
  • Single stage

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine
  • Surgery


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