Management of osteoporosis, fat-soluble vitamin deficiencies, and hyperlipidemia in primary biliary cirrhosis

Cynthia Levy, Keith D. Lindor

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Osteoporosis is several times more common in patients with PBC compared with the general population. Maintaining adequate intake of calcium and vitamin D is important for prevention of bone loss. The use of bisphosphonates or vitamin K to improve bone mineral density in osteopenic patients seems promising and needs to be further evaluated. Patients with PBC may develop fat-soluble vitamin deficiencies, especially vitamins A and D; serum levels should be investigated in patients considered at risk with the aim of recommending appropriate replacement therapy. Finally, hyperlipidemia in PBC does not seem to be associated with an increased risk of atherogenesis. New therapies in this patient population are currently under investigation.

Original languageEnglish
Pages (from-to)901-910
Number of pages10
JournalClinics in Liver Disease
Volume7
Issue number4
DOIs
StatePublished - Nov 1 2003
Externally publishedYes

Fingerprint

Avitaminosis
Biliary Liver Cirrhosis
Hyperlipidemias
Osteoporosis
Fats
Vitamin D
Vitamin K
Diphosphonates
Vitamin A
Bone Density
Population
Atherosclerosis
Calcium
Bone and Bones
Therapeutics
Serum

ASJC Scopus subject areas

  • Hepatology

Cite this

Management of osteoporosis, fat-soluble vitamin deficiencies, and hyperlipidemia in primary biliary cirrhosis. / Levy, Cynthia; Lindor, Keith D.

In: Clinics in Liver Disease, Vol. 7, No. 4, 01.11.2003, p. 901-910.

Research output: Contribution to journalArticle

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