Management of infants with bronchopulmonary dysplasia in North America

Eduardo Bancalari, Deanne Wilson-Costello, Sabine C. Iben

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


The in-hospital management of infants with BPD includes minimizing the duration of mechanical ventilation and avoiding the use of high inspired oxygen concentrations while maintaining adequate oxygenation. Fluid restriction, bronchodilators, and diuretic therapy can improve lung function and reduce the need for supplemental oxygen and high ventilator settings, but do not change the ultimate course of these infants. Corticosteroids also improve lung function and accelerate weaning from oxygen and mechanical ventilation, but their use during the first weeks of life is associated with worse neurological outcome. Adequate nutrition plays an important role in lung injury protection and recovery. Infants with severe BPD frequently develop pulmonary hypertension and may benefit from the use of pulmonary vasodilators. Outpatient management must be carefully planned and carried out by experienced multidisciplinary teams. Social and financial issues must be addressed with the family and caregivers. Home oxygen and mechanical ventilation therapy are used frequently after discharge and require specialized staff and equipment. Maintenance of oxygenation and proper nutritional support are critical aspects in the post-discharge management of these infants. Immunizations and RSV prevention are also important to prevent infections in these vulnerable immunocompromised patients.

Original languageEnglish (US)
Pages (from-to)171-179
Number of pages9
JournalEarly Human Development
Issue number2
StatePublished - Feb 2005


  • Bronchodilators
  • Bronchopulmonary dysplasia
  • Corticosteroids
  • Diuretics
  • Fluid management
  • Home care
  • Mechanical ventilation
  • Outpatient management
  • Oxygen therapy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Management of infants with bronchopulmonary dysplasia in North America'. Together they form a unique fingerprint.

Cite this