Management of cardiovascular risk in the perimenopausal women: A consensus statement of European cardiologists and gynecologists

P. Collins, G. Rosano, C. Casey, C. Daly, M. Gambacciani, P. Hadji, R. Kaaja, T. Mikkola, S. Palacios, Richard A Preston, T. Simon, J. Stevenson, M. Stramba-Badiale

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis and management of cardiovascular risk. Key risk factors that need to be controlled in the perimenopausal woman are hypertension, dyslipidemia, obesity and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older postmenopausal women can be applied to younger perimenopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older postmenopausal women no longer displaying menopausal symptoms. Both gynecologists and cardiovascular physicians have an important role to play in identifying perimenopausal women at risk of cardiovascular morbidity and mortality, and should work as a team to identify and manage risk factors, such as hypertension.

Original languageEnglish
Pages (from-to)508-526
Number of pages19
JournalClimacteric
Volume10
Issue number6
DOIs
StatePublished - Dec 1 2007

Fingerprint

Risk Management
Hormone Replacement Therapy
Women's Health
Hypertension
Dyslipidemias
Menopause
Cardiologists
Epidemiology
Cardiovascular Diseases
Obesity
Hormones
Blood Pressure
Morbidity
Physicians
Mortality

Keywords

  • Cardiology
  • Cardiovascular Prevention
  • Cardiovascular Risk
  • Gynecology
  • Hormones
  • Hypertension
  • Menopause
  • Metabolic Syndrome

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Collins, P., Rosano, G., Casey, C., Daly, C., Gambacciani, M., Hadji, P., ... Stramba-Badiale, M. (2007). Management of cardiovascular risk in the perimenopausal women: A consensus statement of European cardiologists and gynecologists. Climacteric, 10(6), 508-526. https://doi.org/10.1080/13697130701755213

Management of cardiovascular risk in the perimenopausal women : A consensus statement of European cardiologists and gynecologists. / Collins, P.; Rosano, G.; Casey, C.; Daly, C.; Gambacciani, M.; Hadji, P.; Kaaja, R.; Mikkola, T.; Palacios, S.; Preston, Richard A; Simon, T.; Stevenson, J.; Stramba-Badiale, M.

In: Climacteric, Vol. 10, No. 6, 01.12.2007, p. 508-526.

Research output: Contribution to journalArticle

Collins, P, Rosano, G, Casey, C, Daly, C, Gambacciani, M, Hadji, P, Kaaja, R, Mikkola, T, Palacios, S, Preston, RA, Simon, T, Stevenson, J & Stramba-Badiale, M 2007, 'Management of cardiovascular risk in the perimenopausal women: A consensus statement of European cardiologists and gynecologists', Climacteric, vol. 10, no. 6, pp. 508-526. https://doi.org/10.1080/13697130701755213
Collins, P. ; Rosano, G. ; Casey, C. ; Daly, C. ; Gambacciani, M. ; Hadji, P. ; Kaaja, R. ; Mikkola, T. ; Palacios, S. ; Preston, Richard A ; Simon, T. ; Stevenson, J. ; Stramba-Badiale, M. / Management of cardiovascular risk in the perimenopausal women : A consensus statement of European cardiologists and gynecologists. In: Climacteric. 2007 ; Vol. 10, No. 6. pp. 508-526.
@article{3918cbf36b594e6bba59ae27dfeb1664,
title = "Management of cardiovascular risk in the perimenopausal women: A consensus statement of European cardiologists and gynecologists",
abstract = "Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis and management of cardiovascular risk. Key risk factors that need to be controlled in the perimenopausal woman are hypertension, dyslipidemia, obesity and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older postmenopausal women can be applied to younger perimenopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older postmenopausal women no longer displaying menopausal symptoms. Both gynecologists and cardiovascular physicians have an important role to play in identifying perimenopausal women at risk of cardiovascular morbidity and mortality, and should work as a team to identify and manage risk factors, such as hypertension.",
keywords = "Cardiology, Cardiovascular Prevention, Cardiovascular Risk, Gynecology, Hormones, Hypertension, Menopause, Metabolic Syndrome",
author = "P. Collins and G. Rosano and C. Casey and C. Daly and M. Gambacciani and P. Hadji and R. Kaaja and T. Mikkola and S. Palacios and Preston, {Richard A} and T. Simon and J. Stevenson and M. Stramba-Badiale",
year = "2007",
month = "12",
day = "1",
doi = "10.1080/13697130701755213",
language = "English",
volume = "10",
pages = "508--526",
journal = "Climacteric",
issn = "1369-7137",
publisher = "Informa Healthcare",
number = "6",

}

TY - JOUR

T1 - Management of cardiovascular risk in the perimenopausal women

T2 - A consensus statement of European cardiologists and gynecologists

AU - Collins, P.

AU - Rosano, G.

AU - Casey, C.

AU - Daly, C.

AU - Gambacciani, M.

AU - Hadji, P.

AU - Kaaja, R.

AU - Mikkola, T.

AU - Palacios, S.

AU - Preston, Richard A

AU - Simon, T.

AU - Stevenson, J.

AU - Stramba-Badiale, M.

PY - 2007/12/1

Y1 - 2007/12/1

N2 - Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis and management of cardiovascular risk. Key risk factors that need to be controlled in the perimenopausal woman are hypertension, dyslipidemia, obesity and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older postmenopausal women can be applied to younger perimenopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older postmenopausal women no longer displaying menopausal symptoms. Both gynecologists and cardiovascular physicians have an important role to play in identifying perimenopausal women at risk of cardiovascular morbidity and mortality, and should work as a team to identify and manage risk factors, such as hypertension.

AB - Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis and management of cardiovascular risk. Key risk factors that need to be controlled in the perimenopausal woman are hypertension, dyslipidemia, obesity and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older postmenopausal women can be applied to younger perimenopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older postmenopausal women no longer displaying menopausal symptoms. Both gynecologists and cardiovascular physicians have an important role to play in identifying perimenopausal women at risk of cardiovascular morbidity and mortality, and should work as a team to identify and manage risk factors, such as hypertension.

KW - Cardiology

KW - Cardiovascular Prevention

KW - Cardiovascular Risk

KW - Gynecology

KW - Hormones

KW - Hypertension

KW - Menopause

KW - Metabolic Syndrome

UR - http://www.scopus.com/inward/record.url?scp=36749054787&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36749054787&partnerID=8YFLogxK

U2 - 10.1080/13697130701755213

DO - 10.1080/13697130701755213

M3 - Article

C2 - 18049944

AN - SCOPUS:36749054787

VL - 10

SP - 508

EP - 526

JO - Climacteric

JF - Climacteric

SN - 1369-7137

IS - 6

ER -