Management of cardiovascular risk in the peri-menopausal woman: A consensus statement of European cardiologists and gynaecologists

Peter Collins, Guiseppe Rosano, Catherine Casey, Caroline Daly, Marco Gambacciani, Peyman Hadji, Risto Kaaja, Tomi Mikkola, Santiago Palacios, Richard A Preston, Tabassome Simon, John Stevenson, Marco Stramba-Badiale

Research output: Contribution to journalArticle

129 Citations (Scopus)

Abstract

Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis, and management of cardiovascular risk. Key risk factors that need to be controlled in the peri-menopausal woman are hypertension, dyslipidaemia, obesity, and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older post-menopausal women can be applied to younger peri-menopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older post-menopausal women no longer displaying menopausal symptoms. Both gynaecologists and cardiovascular physicians have an important role to play in identifying peri-menopausal women at risk of cardiovascular morbidity and mortality and should work as a team to identify and manage risk factors such as hypertension.

Original languageEnglish
Pages (from-to)2028-2040
Number of pages13
JournalEuropean Heart Journal
Volume28
Issue number16
DOIs
StatePublished - Aug 1 2007

Fingerprint

Risk Management
Hormone Replacement Therapy
Women's Health
Hypertension
Dyslipidemias
Menopause
Cardiologists
Epidemiology
Cardiovascular Diseases
Obesity
Hormones
Blood Pressure
Morbidity
Physicians
Mortality

Keywords

  • Cardiology
  • Cardiovascular prevention
  • Cardiovascular risk
  • Gynaecology
  • Hormones
  • Hypertension
  • Menopause
  • Metabolic syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Collins, P., Rosano, G., Casey, C., Daly, C., Gambacciani, M., Hadji, P., ... Stramba-Badiale, M. (2007). Management of cardiovascular risk in the peri-menopausal woman: A consensus statement of European cardiologists and gynaecologists. European Heart Journal, 28(16), 2028-2040. https://doi.org/10.1093/eurheartj/ehm296

Management of cardiovascular risk in the peri-menopausal woman : A consensus statement of European cardiologists and gynaecologists. / Collins, Peter; Rosano, Guiseppe; Casey, Catherine; Daly, Caroline; Gambacciani, Marco; Hadji, Peyman; Kaaja, Risto; Mikkola, Tomi; Palacios, Santiago; Preston, Richard A; Simon, Tabassome; Stevenson, John; Stramba-Badiale, Marco.

In: European Heart Journal, Vol. 28, No. 16, 01.08.2007, p. 2028-2040.

Research output: Contribution to journalArticle

Collins, P, Rosano, G, Casey, C, Daly, C, Gambacciani, M, Hadji, P, Kaaja, R, Mikkola, T, Palacios, S, Preston, RA, Simon, T, Stevenson, J & Stramba-Badiale, M 2007, 'Management of cardiovascular risk in the peri-menopausal woman: A consensus statement of European cardiologists and gynaecologists', European Heart Journal, vol. 28, no. 16, pp. 2028-2040. https://doi.org/10.1093/eurheartj/ehm296
Collins, Peter ; Rosano, Guiseppe ; Casey, Catherine ; Daly, Caroline ; Gambacciani, Marco ; Hadji, Peyman ; Kaaja, Risto ; Mikkola, Tomi ; Palacios, Santiago ; Preston, Richard A ; Simon, Tabassome ; Stevenson, John ; Stramba-Badiale, Marco. / Management of cardiovascular risk in the peri-menopausal woman : A consensus statement of European cardiologists and gynaecologists. In: European Heart Journal. 2007 ; Vol. 28, No. 16. pp. 2028-2040.
@article{84c8ac02104646019814d29197c8ae51,
title = "Management of cardiovascular risk in the peri-menopausal woman: A consensus statement of European cardiologists and gynaecologists",
abstract = "Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis, and management of cardiovascular risk. Key risk factors that need to be controlled in the peri-menopausal woman are hypertension, dyslipidaemia, obesity, and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older post-menopausal women can be applied to younger peri-menopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older post-menopausal women no longer displaying menopausal symptoms. Both gynaecologists and cardiovascular physicians have an important role to play in identifying peri-menopausal women at risk of cardiovascular morbidity and mortality and should work as a team to identify and manage risk factors such as hypertension.",
keywords = "Cardiology, Cardiovascular prevention, Cardiovascular risk, Gynaecology, Hormones, Hypertension, Menopause, Metabolic syndrome",
author = "Peter Collins and Guiseppe Rosano and Catherine Casey and Caroline Daly and Marco Gambacciani and Peyman Hadji and Risto Kaaja and Tomi Mikkola and Santiago Palacios and Preston, {Richard A} and Tabassome Simon and John Stevenson and Marco Stramba-Badiale",
year = "2007",
month = "8",
day = "1",
doi = "10.1093/eurheartj/ehm296",
language = "English",
volume = "28",
pages = "2028--2040",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "16",

}

TY - JOUR

T1 - Management of cardiovascular risk in the peri-menopausal woman

T2 - A consensus statement of European cardiologists and gynaecologists

AU - Collins, Peter

AU - Rosano, Guiseppe

AU - Casey, Catherine

AU - Daly, Caroline

AU - Gambacciani, Marco

AU - Hadji, Peyman

AU - Kaaja, Risto

AU - Mikkola, Tomi

AU - Palacios, Santiago

AU - Preston, Richard A

AU - Simon, Tabassome

AU - Stevenson, John

AU - Stramba-Badiale, Marco

PY - 2007/8/1

Y1 - 2007/8/1

N2 - Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis, and management of cardiovascular risk. Key risk factors that need to be controlled in the peri-menopausal woman are hypertension, dyslipidaemia, obesity, and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older post-menopausal women can be applied to younger peri-menopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older post-menopausal women no longer displaying menopausal symptoms. Both gynaecologists and cardiovascular physicians have an important role to play in identifying peri-menopausal women at risk of cardiovascular morbidity and mortality and should work as a team to identify and manage risk factors such as hypertension.

AB - Cardiovascular risk is poorly managed in women, especially during the menopausal transition when susceptibility to cardiovascular events increases. Clear gender differences exist in the epidemiology, symptoms, diagnosis, progression, prognosis, and management of cardiovascular risk. Key risk factors that need to be controlled in the peri-menopausal woman are hypertension, dyslipidaemia, obesity, and other components of the metabolic syndrome, with the avoidance and careful control of diabetes. Hypertension is a particularly powerful risk factor and lowering of blood pressure is pivotal. Hormone replacement therapy is acknowledged as the gold standard for the alleviation of the distressing vasomotor symptoms of the menopause, but the findings of the Women's Health Initiative (WHI) study generated concern for the detrimental effect on cardiovascular events. Thus, hormone replacement therapy cannot be recommended for the prevention of cardiovascular disease. Whether the findings of WHI in older post-menopausal women can be applied to younger peri-menopausal women is unknown. It is increasingly recognized that hormone therapy is inappropriate for older post-menopausal women no longer displaying menopausal symptoms. Both gynaecologists and cardiovascular physicians have an important role to play in identifying peri-menopausal women at risk of cardiovascular morbidity and mortality and should work as a team to identify and manage risk factors such as hypertension.

KW - Cardiology

KW - Cardiovascular prevention

KW - Cardiovascular risk

KW - Gynaecology

KW - Hormones

KW - Hypertension

KW - Menopause

KW - Metabolic syndrome

UR - http://www.scopus.com/inward/record.url?scp=35348834293&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35348834293&partnerID=8YFLogxK

U2 - 10.1093/eurheartj/ehm296

DO - 10.1093/eurheartj/ehm296

M3 - Article

C2 - 17644507

AN - SCOPUS:35348834293

VL - 28

SP - 2028

EP - 2040

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

IS - 16

ER -