Management of advanced laryngeal and hypopharyngeal plexiform neurofibroma in adults

Sandeep P. Dave, Uzma Farooq, Francisco J. Civantos

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Laryngeal neurofibromas are rare. The plexiform subtype is less common and often presents during childhood in association with neurofibromatosis type I. Because it is unencapsulated and more aggressive, plexiform neurofibroma presents a management dilemma. Imaging, particularly magnetic resonance imaging, can aid in diagnosing neurofibroma, differentiating the nonplexiform and plexiform subtypes, and planning the subsequent operative approach. The importance of conservative surgery to relieve symptoms, but preserve laryngopharyngeal function, and close follow-up are stressed. We report 2 adult cases of plexiform neurofibroma involving the larynx and hypopharynx and discuss the controversies in management.

Original languageEnglish (US)
Pages (from-to)279-283
Number of pages5
JournalAmerican Journal of Otolaryngology - Head and Neck Medicine and Surgery
Issue number4
StatePublished - Jul 2008

ASJC Scopus subject areas

  • Otorhinolaryngology


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