Short-course, especially 3-day, regimens are gaining increasing popularity in the treatment of acute uncomplicated cystitis in young adult women. Acute uncomplicated pyelonephritis occurring in the otherwise healthy young woman who has not been recently instrumented or treated with antimicrobials and who has no known genitourinary tract abnormalities may or may not require hospitalization, and generally responds to a 14-day antimicrobial regimen. Women with frequently recurring urinary tract infection can be successfully managed with continuous or postcoital prophylaxis or with early selfadministration of antimicrobials. Short-course regimens are not indicated in men with acute cystitis because of the relatively greater likelihood of treatment failure.
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