Mallory Weiss syndrome is not associated with hiatal hernia: a matched case–control study

Juan E. Corral; Tara Keihanian; Paul T. Kröner; Ryan Dauer; Frank J. Lukens; Daniel A Sussman

doi:10.1080/00365521.2016.1267793

Mallory Weiss syndrome is not associated with hiatal hernia: a matched case–control study

Juan E. Corral, Tara Keihanian, Paul T. Kröner, Ryan Dauer, Frank J. Lukens, Daniel A Sussman

Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Background/objective: Hiatal hernia is considered to be a predisposing factor to develop Mallory-Weiss Syndrome (MWS). No large case–control studies verifying this hypothesis have been conducted. Methods: We reviewed all esophagogastroduodenoscopies with findings of MWS (n = 2342) in a national database and compared with age and gender-matched controls (n = 9368). Demographics, endoscopic characteristics and presence of a hiatal hernia were compared between both groups. Average age was 56.7 ± 18.6 years, and 72.4% were male. Results: Hiatal hernia was more common in controls, and no significant difference was seen in a multivariate analysis. Conclusion: Dynamic changes inducing mucosal tension are more relevant determinants to develop MWS than gastro-esophageal junction location alone.

Original language	English (US)
Pages (from-to)	462-464
Number of pages	3
Journal	Scandinavian Journal of Gastroenterology
Volume	52
Issue number	4
DOIs	https://doi.org/10.1080/00365521.2016.1267793
State	Published - Apr 3 2017

Keywords

esophagus
gastrointestinal bleeding
hiatal hernia
Mallory Weiss

ASJC Scopus subject areas

Medicine(all)
Gastroenterology

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10.1080/00365521.2016.1267793

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title = "Mallory Weiss syndrome is not associated with hiatal hernia: a matched case–control study",

abstract = "Background/objective: Hiatal hernia is considered to be a predisposing factor to develop Mallory-Weiss Syndrome (MWS). No large case–control studies verifying this hypothesis have been conducted. Methods: We reviewed all esophagogastroduodenoscopies with findings of MWS (n = 2342) in a national database and compared with age and gender-matched controls (n = 9368). Demographics, endoscopic characteristics and presence of a hiatal hernia were compared between both groups. Average age was 56.7 ± 18.6 years, and 72.4% were male. Results: Hiatal hernia was more common in controls, and no significant difference was seen in a multivariate analysis. Conclusion: Dynamic changes inducing mucosal tension are more relevant determinants to develop MWS than gastro-esophageal junction location alone.",

keywords = "esophagus, gastrointestinal bleeding, hiatal hernia, Mallory Weiss",

author = "Corral, {Juan E.} and Tara Keihanian and Kr{\"o}ner, {Paul T.} and Ryan Dauer and Lukens, {Frank J.} and Sussman, {Daniel A}",

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T2 - a matched case–control study

AU - Corral, Juan E.

AU - Keihanian, Tara

AU - Kröner, Paul T.

AU - Dauer, Ryan

AU - Lukens, Frank J.

AU - Sussman, Daniel A

PY - 2017/4/3

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N2 - Background/objective: Hiatal hernia is considered to be a predisposing factor to develop Mallory-Weiss Syndrome (MWS). No large case–control studies verifying this hypothesis have been conducted. Methods: We reviewed all esophagogastroduodenoscopies with findings of MWS (n = 2342) in a national database and compared with age and gender-matched controls (n = 9368). Demographics, endoscopic characteristics and presence of a hiatal hernia were compared between both groups. Average age was 56.7 ± 18.6 years, and 72.4% were male. Results: Hiatal hernia was more common in controls, and no significant difference was seen in a multivariate analysis. Conclusion: Dynamic changes inducing mucosal tension are more relevant determinants to develop MWS than gastro-esophageal junction location alone.

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