Abstract
Malignant gliomas are the most common type of primary malignant brain tumor, and glioblastoma is the most common malignant glioma. Standard initial therapy for glioblastoma includes aggressive surgical resection followed by a combination of focal radiation and chemotherapy with temozolomide; the role for chemotherapy in initial treatment of other malignant gliomas is less clear. Prognosis is poor, and recurrence of any malignant glioma is almost universal. This chapter provides an overview of malignant gliomas, their treatment, and ongoing research looking for more effective treatments.
| Original language | English (US) |
|---|---|
| Title of host publication | Neuro-oncology |
| Subtitle of host publication | First Edition |
| Publisher | Blackwell Publishing Ltd |
| Pages | 61-75 |
| Number of pages | 15 |
| ISBN (Print) | 9780470655757 |
| DOIs | |
| State | Published - Feb 29 2012 |
| Externally published | Yes |
Keywords
- Anaplastic astrocytoma
- Anaplastic oligodendroglioma
- Bevacizumab
- Chemotherapy
- Glioblastoma
- Malignant glioma
- Pseudoprogression
- Radiation therapy
- Surgery
- Temozolomide
ASJC Scopus subject areas
- Neuroscience(all)
- Medicine(all)