Abstract
One hundred fifteen subjects took part in a double-blind study comparing the efficacy and safety of 0.5% malathion lotion (Prioderm lotion) and the alcoholic vehicle of the lotion as pediculicides in the treatment of head lice. The subjects, with a mean age of 9 years, had long-standing lice infestations and at least 20 viable ova. The subjects were treated with the test preparation, which was allowed to remain on the hair for 12 hours. Ovicidal and pediculicidal efficacy for the malathion lotion was significant; overall clinical evaluation by the investigators showed a significant number of moderate to marked therapeutic responses to malathion lotion. Only one adverse reaction (in the malathion lotion group) was reported, the stinging of pyodermal lesions in reaction to the alcoholic vehicle. Other concomitant scalp diseases were unchanged or improved at the end of the study.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3103-3105 |
| Number of pages | 3 |
| Journal | JAMA - Journal of the American Medical Association |
| Volume | 247 |
| Issue number | 22 |
| DOIs | |
| State | Published - Jun 11 1982 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Malathion for Treatment of Pediculus humanus var capitis Infestation. / Taplin, David; Castillero, Pedro M.; Spiegel, Joan; Mercer, Scott; Rivera, Alicio A.; Schachner, Lawrence A.
In: JAMA - Journal of the American Medical Association, Vol. 247, No. 22, 11.06.1982, p. 3103-3105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Malathion for Treatment of Pediculus humanus var capitis Infestation
AU - Taplin, David
AU - Castillero, Pedro M.
AU - Spiegel, Joan
AU - Mercer, Scott
AU - Rivera, Alicio A.
AU - Schachner, Lawrence A
PY - 1982/6/11
Y1 - 1982/6/11
N2 - One hundred fifteen subjects took part in a double-blind study comparing the efficacy and safety of 0.5% malathion lotion (Prioderm lotion) and the alcoholic vehicle of the lotion as pediculicides in the treatment of head lice. The subjects, with a mean age of 9 years, had long-standing lice infestations and at least 20 viable ova. The subjects were treated with the test preparation, which was allowed to remain on the hair for 12 hours. Ovicidal and pediculicidal efficacy for the malathion lotion was significant; overall clinical evaluation by the investigators showed a significant number of moderate to marked therapeutic responses to malathion lotion. Only one adverse reaction (in the malathion lotion group) was reported, the stinging of pyodermal lesions in reaction to the alcoholic vehicle. Other concomitant scalp diseases were unchanged or improved at the end of the study.
AB - One hundred fifteen subjects took part in a double-blind study comparing the efficacy and safety of 0.5% malathion lotion (Prioderm lotion) and the alcoholic vehicle of the lotion as pediculicides in the treatment of head lice. The subjects, with a mean age of 9 years, had long-standing lice infestations and at least 20 viable ova. The subjects were treated with the test preparation, which was allowed to remain on the hair for 12 hours. Ovicidal and pediculicidal efficacy for the malathion lotion was significant; overall clinical evaluation by the investigators showed a significant number of moderate to marked therapeutic responses to malathion lotion. Only one adverse reaction (in the malathion lotion group) was reported, the stinging of pyodermal lesions in reaction to the alcoholic vehicle. Other concomitant scalp diseases were unchanged or improved at the end of the study.
UR - http://www.scopus.com/inward/record.url?scp=84944368854&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84944368854&partnerID=8YFLogxK
U2 - 10.1001/jama.1982.03320470049031
DO - 10.1001/jama.1982.03320470049031
M3 - Article
C2 - 7043013
AN - SCOPUS:84944368854
VL - 247
SP - 3103
EP - 3105
JO - JAMA - Journal of the American Medical Association
JF - JAMA - Journal of the American Medical Association
SN - 0002-9955
IS - 22
ER -