Magnetic resonance imaging correlates of executive function impairments in multiple sclerosis

Steven J. Huber, Robert A. Bornstein, Kottil W. Rammohan, Jeffrey A. Christy, Donald W. Chakeres, Robert B. McGhee

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Frontal lobe lesions may play an integral role in cognitive impairments associated with multiple sclerosis (MS). Executive function impairments, traditionally linked to frontal lobe lesions, are common neuropsychological deficits in MS. We found that executive functions were related to left frontal lesions, and to the total brain lesion area. This pattern suggests that left frontal lesions and/or disruption of the pathways to the left frontal lobe have a role in these disturbances in MS.

Original languageEnglish (US)
Pages (from-to)33-36
Number of pages4
JournalNeuropsychiatry, Neuropsychology and Behavioral Neurology
Volume5
Issue number1
StatePublished - Jan 1992
Externally publishedYes

Keywords

  • Executive function
  • Magnetic resonance imaging
  • Multiple sclerosis

ASJC Scopus subject areas

  • Psychology(all)
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health

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