Macular retinal pigment epithelial clumping leading to a diagnosis of FEVR

Rebecca Tanenbaum, Dhariana Acon, Ana Rodriguez, Catherin Negron, Audina Berrocal

Research output: Contribution to journalArticlepeer-review

Abstract

Familial exudative vitreoretinopathy (FEVR) is a rare hereditary disorder characterized by abnormal or incomplete retinal angiogenesis. The peripheral avascularity, irregular neovascularization, and vascular leakage seen in FEVR are similar to changes that may be seen in retinopathy of prematurity (ROP). The authors report a case of atypical macular pigment clumping leading to the diagnosis of ROPER (ie, ROP vs FEVR) in a premature infant born at 23 weeks of gestation with a birth weight of 451 grams, who presented with atypical aggressive posterior ROP and a heterozygous variant in the LRP5 gene.

Original languageEnglish (US)
Pages (from-to)505-508
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume52
Issue number9
DOIs
StatePublished - Sep 2021

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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