Macular morphology assessed by optical coherence tomography image segmentation after femtosecond laser-assisted and standard cataract surgery

Zoltán Z. Nagy, Monika Ecsedy, Illés Kovács, Ágnes Takács, Erika Tátrai, Gábor Márk Somfai, Delia Cabrera DeBuc

Research output: Contribution to journalArticle

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Abstract

Purpose: To evaluate and compare thickness changes in the retinal layers in the macula with optical coherence tomography (OCT) segmentation software after femtosecond laser-assisted phacoemulsification (study group) and conventional phacoemulsification (control group). Setting: Department of Ophthalmology, Semmelweis University, Budapest, Hungary. Design: Case-control study. Methods: Total retinal thickness of the macula was evaluated using Stratus OCT 4 to 8 weeks postoperatively. The OCT images were segmented using OCT retinal image analysis software. Regional thickness data in the central area, inner rings, and outer rings were obtained and absolute and relative thicknesses of the individual retinal layers in the 2 study groups compared. Relative thickness was calculated as the ratio of the retinal layer to the total retinal thickness. Results: All surgeries were uneventful. Statistically significant differences were found in absolute outer nuclear layer thickness and relative outer nuclear layer thickness in the inner and outer macular rings between the 2 groups. After adjusting for effective phaco time in multivariate modeling, type of surgery showed a significantly lower relative outer nuclear layer ratio in the inner retinal ring (0.26 with 95% confidence interval [CI], 0.25-0.27 versus 0.28 with 95% CI, 0.27-0.29; P=.03) and in the outer retinal ring (0.27 with 95% CI, 0.25-0.28 versus 0.29 with 95% CI, 0.28-0.31; P=.02) in the study group. Conclusion: After cataract surgery, macular edema was detectable mainly in the outer nuclear layer in both groups but was significantly less using the femtosecond laser platform.

Original languageEnglish
Pages (from-to)941-946
Number of pages6
JournalJournal of Cataract and Refractive Surgery
Volume38
Issue number6
DOIs
StatePublished - Jun 1 2012

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Optical Coherence Tomography
Cataract
Lasers
Confidence Intervals
Phacoemulsification
Software
Macular Edema
Hungary
Ophthalmology
Case-Control Studies
Control Groups

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Surgery

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Macular morphology assessed by optical coherence tomography image segmentation after femtosecond laser-assisted and standard cataract surgery. / Nagy, Zoltán Z.; Ecsedy, Monika; Kovács, Illés; Takács, Ágnes; Tátrai, Erika; Somfai, Gábor Márk; Cabrera DeBuc, Delia.

In: Journal of Cataract and Refractive Surgery, Vol. 38, No. 6, 01.06.2012, p. 941-946.

Research output: Contribution to journalArticle

Nagy, Zoltán Z. ; Ecsedy, Monika ; Kovács, Illés ; Takács, Ágnes ; Tátrai, Erika ; Somfai, Gábor Márk ; Cabrera DeBuc, Delia. / Macular morphology assessed by optical coherence tomography image segmentation after femtosecond laser-assisted and standard cataract surgery. In: Journal of Cataract and Refractive Surgery. 2012 ; Vol. 38, No. 6. pp. 941-946.
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abstract = "Purpose: To evaluate and compare thickness changes in the retinal layers in the macula with optical coherence tomography (OCT) segmentation software after femtosecond laser-assisted phacoemulsification (study group) and conventional phacoemulsification (control group). Setting: Department of Ophthalmology, Semmelweis University, Budapest, Hungary. Design: Case-control study. Methods: Total retinal thickness of the macula was evaluated using Stratus OCT 4 to 8 weeks postoperatively. The OCT images were segmented using OCT retinal image analysis software. Regional thickness data in the central area, inner rings, and outer rings were obtained and absolute and relative thicknesses of the individual retinal layers in the 2 study groups compared. Relative thickness was calculated as the ratio of the retinal layer to the total retinal thickness. Results: All surgeries were uneventful. Statistically significant differences were found in absolute outer nuclear layer thickness and relative outer nuclear layer thickness in the inner and outer macular rings between the 2 groups. After adjusting for effective phaco time in multivariate modeling, type of surgery showed a significantly lower relative outer nuclear layer ratio in the inner retinal ring (0.26 with 95{\%} confidence interval [CI], 0.25-0.27 versus 0.28 with 95{\%} CI, 0.27-0.29; P=.03) and in the outer retinal ring (0.27 with 95{\%} CI, 0.25-0.28 versus 0.29 with 95{\%} CI, 0.28-0.31; P=.02) in the study group. Conclusion: After cataract surgery, macular edema was detectable mainly in the outer nuclear layer in both groups but was significantly less using the femtosecond laser platform.",
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AU - Tátrai, Erika

AU - Somfai, Gábor Márk

AU - Cabrera DeBuc, Delia

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N2 - Purpose: To evaluate and compare thickness changes in the retinal layers in the macula with optical coherence tomography (OCT) segmentation software after femtosecond laser-assisted phacoemulsification (study group) and conventional phacoemulsification (control group). Setting: Department of Ophthalmology, Semmelweis University, Budapest, Hungary. Design: Case-control study. Methods: Total retinal thickness of the macula was evaluated using Stratus OCT 4 to 8 weeks postoperatively. The OCT images were segmented using OCT retinal image analysis software. Regional thickness data in the central area, inner rings, and outer rings were obtained and absolute and relative thicknesses of the individual retinal layers in the 2 study groups compared. Relative thickness was calculated as the ratio of the retinal layer to the total retinal thickness. Results: All surgeries were uneventful. Statistically significant differences were found in absolute outer nuclear layer thickness and relative outer nuclear layer thickness in the inner and outer macular rings between the 2 groups. After adjusting for effective phaco time in multivariate modeling, type of surgery showed a significantly lower relative outer nuclear layer ratio in the inner retinal ring (0.26 with 95% confidence interval [CI], 0.25-0.27 versus 0.28 with 95% CI, 0.27-0.29; P=.03) and in the outer retinal ring (0.27 with 95% CI, 0.25-0.28 versus 0.29 with 95% CI, 0.28-0.31; P=.02) in the study group. Conclusion: After cataract surgery, macular edema was detectable mainly in the outer nuclear layer in both groups but was significantly less using the femtosecond laser platform.

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