Macular hole surgery without using adjunctive additives

W. E. Smiddy, S. Pimentel, G. A. Williams

Research output: Contribution to journalArticlepeer-review


Purpose. To evaluate the efficacy of macular hole surgical techniques without using adjunctive additives. Methods. Prospective study of eyes operated consecutively in two centers for macular holes with duration of one year or less and no previous vitreous surgery. Surgical technique was similar to standard techniques, but included preretinal membrane dissection around edges of macular hole. No adjvants were added. Long-acting internal gas tamponade and posturing were used. Best corrected visual acuity, improvement in visual acuity, and hole flattening were determined. Results. Postoperatively flattening of the hole was induced in 39 of 43 (91%) eyes with at least a halving of the visual angle (3 line visual increase) in 51%, and vision of 20/40 or better in 56% over the 5.5 month follow-up interval. Conclusions. The success rate of current macular hole surgical techniques suggest that adjunctive additives may not be necessary for most cases, and emphasize the need for evaluating new treatment modalities with controlled clinical trials including well defined endpoints.

Original languageEnglish (US)
Pages (from-to)S474
JournalInvestigative Ophthalmology and Visual Science
Issue number3
StatePublished - Feb 15 1996
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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