Abstract
Macular and paramacular electroretinograms in response to two adjacent checks (6 deg/side), alternating at constant mean luminance, were recorded in 34 normal subjects ranging in age from 16 to 74 years. The macular electroretinogram declines progressively in amplitude with age (R = -0.42; P = 0.013). The amplitude ratio between macular and paramacular responses tends to be independent of age (R = -0.21; P = 0.22). Age-related changes in the macular electroretinogram shown in our study are consistent with previous anatomical and functional studies, which indicate a deterioration of photoreceptors beyond 20 years of age. These results suggest a possible use of this technique for future studies on macular degeneration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 37-43 |
| Number of pages | 7 |
| Journal | Documenta Ophthalmologica |
| Volume | 70 |
| Issue number | 1 |
| DOIs | |
| State | Published - Sep 1 1988 |
| Externally published | Yes |
Keywords
- age
- macular electroretinogram
- standard techniques
ASJC Scopus subject areas
- Ophthalmology
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Cite this
Bagolini, B., Porciatti, V., Falsini, B., Scalia, G., Neroni, M., & Moretti, G. (1988). Macular electroretinogram as a function of age of subjects. Documenta Ophthalmologica, 70(1), 37-43. https://doi.org/10.1007/BF00154734