Abstract
Macular and paramacular electroretinograms in response to two adjacent checks (6 deg/side), alternating at constant mean luminance, were recorded in 34 normal subjects ranging in age from 16 to 74 years. The macular electroretinogram declines progressively in amplitude with age (R = -0.42; P = 0.013). The amplitude ratio between macular and paramacular responses tends to be independent of age (R = -0.21; P = 0.22). Age-related changes in the macular electroretinogram shown in our study are consistent with previous anatomical and functional studies, which indicate a deterioration of photoreceptors beyond 20 years of age. These results suggest a possible use of this technique for future studies on macular degeneration.
| Original language | English |
|---|---|
| Pages (from-to) | 37-43 |
| Number of pages | 7 |
| Journal | Documenta Ophthalmologica |
| Volume | 70 |
| Issue number | 1 |
| DOIs | |
| State | Published - Sep 1 1988 |
| Externally published | Yes |
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Keywords
- age
- macular electroretinogram
- standard techniques
ASJC Scopus subject areas
- Ophthalmology
Cite this
Macular electroretinogram as a function of age of subjects. / Bagolini, B.; Porciatti, Vittorio; Falsini, B.; Scalia, G.; Neroni, M.; Moretti, G.
In: Documenta Ophthalmologica, Vol. 70, No. 1, 01.09.1988, p. 37-43.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Macular electroretinogram as a function of age of subjects
AU - Bagolini, B.
AU - Porciatti, Vittorio
AU - Falsini, B.
AU - Scalia, G.
AU - Neroni, M.
AU - Moretti, G.
PY - 1988/9/1
Y1 - 1988/9/1
N2 - Macular and paramacular electroretinograms in response to two adjacent checks (6 deg/side), alternating at constant mean luminance, were recorded in 34 normal subjects ranging in age from 16 to 74 years. The macular electroretinogram declines progressively in amplitude with age (R = -0.42; P = 0.013). The amplitude ratio between macular and paramacular responses tends to be independent of age (R = -0.21; P = 0.22). Age-related changes in the macular electroretinogram shown in our study are consistent with previous anatomical and functional studies, which indicate a deterioration of photoreceptors beyond 20 years of age. These results suggest a possible use of this technique for future studies on macular degeneration.
AB - Macular and paramacular electroretinograms in response to two adjacent checks (6 deg/side), alternating at constant mean luminance, were recorded in 34 normal subjects ranging in age from 16 to 74 years. The macular electroretinogram declines progressively in amplitude with age (R = -0.42; P = 0.013). The amplitude ratio between macular and paramacular responses tends to be independent of age (R = -0.21; P = 0.22). Age-related changes in the macular electroretinogram shown in our study are consistent with previous anatomical and functional studies, which indicate a deterioration of photoreceptors beyond 20 years of age. These results suggest a possible use of this technique for future studies on macular degeneration.
KW - age
KW - macular electroretinogram
KW - standard techniques
UR - http://www.scopus.com/inward/record.url?scp=0023796676&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023796676&partnerID=8YFLogxK
U2 - 10.1007/BF00154734
DO - 10.1007/BF00154734
M3 - Article
VL - 70
SP - 37
EP - 43
JO - Documenta Ophthalmologica
JF - Documenta Ophthalmologica
SN - 0012-4486
IS - 1
ER -