Lymphoid involvement in a patient with acute myeloid leukemia: A direct phenotypic and genotypic study of single cells

Wa'el El-Rifai, Marcelo L. Larramendy, Tapani Ruutu, Sakari Knuutila

Research output: Contribution to journalArticle

5 Scopus citations


Lymphoid involvement in acute myeloid leukemia (AML) was studied using the morphology-antibody-chromosome (MAC) combination technique in one patient. The chromosomal aberration, trisomy 8, was demonstrated in AML blasts, glycophorin A-positive erythroblasts, and CD3- and CD20/22-positive small lymphocytes. This suggests that in this patient even lymphocytes belonged to the leukemic clone.

Original languageEnglish (US)
Pages (from-to)34-37
Number of pages4
JournalGenes Chromosomes and Cancer
Issue number1
StatePublished - Jan 1 1996


ASJC Scopus subject areas

  • Genetics
  • Cancer Research

Cite this