Luteinizing hormone-releasing hormone (LH-RH) content of the hypothalamic nuclei in rat

M. Palkovits; A. Arimura; M. Brownstein; A. V. Schally; J. M. Saavedra

doi:10.1210/endo-95-2-554

Luteinizing hormone-releasing hormone (LH-RH) content of the hypothalamic nuclei in rat

M. Palkovits, A. Arimura, M. Brownstein, A. V. Schally, J. M. Saavedra

Pathology

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Abstract

The luteinizing hormone releasing hormone (LH RH) content of 16 separate hypothalamic nuclei and of the median eminence have been determined by radioimmunoassay in the rat. High concentrations of LH RH were measured in the median eminence and in the arcuate nucleus. Other nuclei of the hypothalamus, as well as the medial preoptic nucleus, contained little or no LH RH. The amount of LH/RH stored in the median eminence is about twice that found in the arcuate nucleus, but the concentration in the median eminence is 7.7 times higher than in the arcuate nucleus. Within the arcuate nucleus 73% of the LH RH is present in the middle part (NA III) of the nucleus.

Original language	English (US)
Pages (from-to)	554-558
Number of pages	5
Journal	Endocrinology
Volume	95
Issue number	2
DOIs	https://doi.org/10.1210/endo-95-2-554
State	Published - Aug 1974

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Endocrinology

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Palkovits, M., Arimura, A., Brownstein, M., Schally, A. V., & Saavedra, J. M. (1974). Luteinizing hormone-releasing hormone (LH-RH) content of the hypothalamic nuclei in rat. Endocrinology, 95(2), 554-558. https://doi.org/10.1210/endo-95-2-554

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10.1210/endo-95-2-554