Luteinizing hormone-releasing hormone (LH-RH) content of the hypothalamic nuclei in rat

M. Palkovits, A. Arimura, M. Brownstein, A. V. Schally, J. M. Saavedra

Research output: Contribution to journalArticlepeer-review

137 Scopus citations


The luteinizing hormone releasing hormone (LH RH) content of 16 separate hypothalamic nuclei and of the median eminence have been determined by radioimmunoassay in the rat. High concentrations of LH RH were measured in the median eminence and in the arcuate nucleus. Other nuclei of the hypothalamus, as well as the medial preoptic nucleus, contained little or no LH RH. The amount of LH/RH stored in the median eminence is about twice that found in the arcuate nucleus, but the concentration in the median eminence is 7.7 times higher than in the arcuate nucleus. Within the arcuate nucleus 73% of the LH RH is present in the middle part (NA III) of the nucleus.

Original languageEnglish (US)
Pages (from-to)554-558
Number of pages5
Issue number2
StatePublished - Aug 1974
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology


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