Estado actual del trasplante pulmonar

Translated title of the contribution: Lung transplantation. State of the art

Lisardo García-Covarrubias, Tomas A. Salerno, Anthony Panos, Si M. Pham

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Lung transplantation is currently considered an established treatment for some advanced lung diseases. The beginning of experimental lung transplantation dates back to the 1940's when the Soviet Vladimir P. Demikhov performed the first lung transplants in animals. Two decades later, James Hardy performed the first lung transplant in humans. Unfortunately, the beginning of clinical lung transplantation was hampered by technical complications and the excessive toxicity of immunosuppressive drugs. Improvement in the surgical technique along with the development of more effective and less toxic immunosuppressive drugs has led to a better outcome in lunt transplant recipients. Donor selection and management before organ procurement play a key role in the receptor's outcome. Due to the shortage of donors, some institutions are using more liberal selection criteria, reporting satisfactory outcomes. The approach of the lung and heart-lung transplant patient is multidisciplinary and includes the cardiothoracic transplant surgeon, pulmonologist, anesthesiologist, and intensivist, among others. Herein, we review some relevant historical aspects and recent advances in the management of lung transplant recipients, including indications and contraindications, evaluation of donors and recipients, surgical techniques and peripost-operative care.

Translated title of the contributionLung transplantation. State of the art
Original languageSpanish
Pages (from-to)323-332
Number of pages10
JournalGaceta medica de Mexico
Volume143
Issue number4
StatePublished - Dec 1 2007

Keywords

  • Advances
  • Indications
  • Lung
  • Management
  • Transplantation

ASJC Scopus subject areas

  • Medicine(all)

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    García-Covarrubias, L., Salerno, T. A., Panos, A., & Pham, S. M. (2007). Estado actual del trasplante pulmonar. Gaceta medica de Mexico, 143(4), 323-332.