Lung compliance in newborns with patent ductus arteriosus before and after surgical ligation

T. Gerhardt, E. Bancalari

Research output: Contribution to journalArticle

79 Scopus citations

Abstract

Pressure volume curves of the lungs were determined in 10 premature infants (mean gestational age 31.4 weeks, mean birth weight 1,260 g) before and after surgical ligation of a patent ductus arteriosus (PDA). 7 infants who had low compliance initially showed a significant improvement in lung compliance after surgery, while 3 infants whose compliance was close to normal before surgery had a decrease after ligation. In conclusion, a PDA with left to right shunt is frequently associated with a decrease in lung compliance that improves after ligation. Measurement of lung compliance in infants with PDA can be helpful in predicting the degree of improvement in lung function that may result from the closure of the ductus.

Original languageEnglish (US)
Pages (from-to)96-105
Number of pages10
JournalBiology of the Neonate
Volume38
Issue number1-2
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Biology

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