Lung cancer in patients with human immunodeficiency virus infection

M. R. Flores, K. S. Sridhar, R. J. Thurer, M. Saldana, W. A. Raub, N. G. Klimas

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

This retrospective study determined the clinical course of lung cancer in patients with human immunodeficiency virus (IIIV) infection. A total of 23 patients with HIV infection archived as lung cancer were studied: 16 were identified from about 1,000 lung cancer patients entered in the tumor registry and medical records of Jackson Memorial Hospital, 7 were identified from about 1,000 HIV-positive patients entered in the Special Immunology registry of Veterans Administration Medical Center, 4 patients did not have pathologic confirmation of lung cancer, and 19 patients, all men, met the criteria for analysis (histopathologic diagnosis of lung cancer and HIV+ by serology). The median age was 47 (range: 3666). Risk factors for HIV were homosexuality (6 patients), blood transfusion (3), promiscuity (5), intravenous drug abuse (4), and none (3). Six patients had a history of coexistent pulmonary tuberculosis and 5 had Pneumocystis carinii pneumonia. Median survival from diagnosis of lung cancer was 3 months. Advanced stages of both HIV infection and lung cancer may account for the poor survival. All patients were men and noted to be younger than other patients with lung cancer.

Original languageEnglish (US)
Pages (from-to)59-66
Number of pages8
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Volume18
Issue number1
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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