Low pack pain in Paget's disease of bone

Roy D Altman, Mark Brown, F. Gargano

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Clinical and laboratory evaluation with bone scan, radiography, and computed tomography were performed on 25 patients with severe Paget's disease of bone and low back pain. Back pain was classified as caused by Paget's disease in only three patients. The remaining 22 patients had coexistent Paget's disease and osteoarthritis. There was difficulty separating the cause of back pain in those patients with coexistent Paget's disease and osteoarthritis, even when the diseases were present at different levels of the spine. The pathogenesis of Paget's disease appears to precipitate osteoarthritis and several low back syndromes. Suppressive therapy with disodium etidronate (EHDP) for Paget's disease was of benefit in eight of 22 patients (36%) with identifiable osteoarthritis. It is suggested that EHDP and perhaps other suppressive agents for Paget's disease receive limited use in patients with back pain unless a defined pagetic lesion appears related to the clinical syndrome in the absence of identifiable osteoarthritis.

Original languageEnglish
Pages (from-to)152-161
Number of pages10
JournalClinical Orthopaedics and Related Research
VolumeNo. 217
StatePublished - Jan 1 1987

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Osteitis Deformans
Osteoarthritis
Pain
Etidronic Acid
Back Pain
Low Back Pain
Radiography
Spine
Tomography
Bone and Bones

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Low pack pain in Paget's disease of bone. / Altman, Roy D; Brown, Mark; Gargano, F.

In: Clinical Orthopaedics and Related Research, Vol. No. 217, 01.01.1987, p. 152-161.

Research output: Contribution to journalArticle

Altman, RD, Brown, M & Gargano, F 1987, 'Low pack pain in Paget's disease of bone', Clinical Orthopaedics and Related Research, vol. No. 217, pp. 152-161.
Altman, Roy D ; Brown, Mark ; Gargano, F. / Low pack pain in Paget's disease of bone. In: Clinical Orthopaedics and Related Research. 1987 ; Vol. No. 217. pp. 152-161.
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