Low coherence interferometer for sensing retardance change during neural activity.

Muhammad K. Al-Kaisi; David Landowne; Taner Akkin

Low coherence interferometer for sensing retardance change during neural activity.

Muhammad K. Al-Kaisi, David Landowne, Taner Akkin

Research output: Contribution to journal › Article › peer-review

Abstract

A variety of optical measurements, including retardance/birefringence change, have revealed transient optical and structural changes associated with action potential propagation. Those changes can be understood better by developing new techniques and improving the current approaches. To detect transient retardance changes in a stimulated nerve, we propose a differential phase technique utilizing two orthogonal polarization channels of a polarization-maintaining fiber based interferometer. The superior sensitivity of the system (10.4 pm) is promising to achieve a non-contact optical measurement of action potential propagation in reflection mode, and to study the transient retardance changes during neural activity.

Original language	English
Pages (from-to)	6318-6320
Number of pages	3
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
State	Published - Dec 1 2009
Externally published	Yes

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

Cite this

Low coherence interferometer for sensing retardance change during neural activity. / Al-Kaisi, Muhammad K.; Landowne, David; Akkin, Taner.

In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 01.12.2009, p. 6318-6320.

Research output: Contribution to journal › Article › peer-review

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AB - A variety of optical measurements, including retardance/birefringence change, have revealed transient optical and structural changes associated with action potential propagation. Those changes can be understood better by developing new techniques and improving the current approaches. To detect transient retardance changes in a stimulated nerve, we propose a differential phase technique utilizing two orthogonal polarization channels of a polarization-maintaining fiber based interferometer. The superior sensitivity of the system (10.4 pm) is promising to achieve a non-contact optical measurement of action potential propagation in reflection mode, and to study the transient retardance changes during neural activity.

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ER -

Low coherence interferometer for sensing retardance change during neural activity.

Abstract

ASJC Scopus subject areas

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