Loss of reactivity of the pulmonary vascular bed in primary pulmonary hypertension

Philip Samet, William H. Bernstein

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A follow-up case report of primary pulmonary hypertension is described. In 1959, intracardiac infusion of acetylcholine resulted in a considerable decrease in pulmonary arterial pressure both at rest and during exercise. In 1962, acetylcholine failed to elicit a decrement in pulmonary arterial pressure, demonstrating a loss of vasodilator reactivity of the pulmonary vascular bed over this period of time.

Original languageEnglish
Pages (from-to)197-199
Number of pages3
JournalAmerican Heart Journal
Volume66
Issue number2
StatePublished - Aug 1 1963
Externally publishedYes

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Blood Vessels
Lung
Acetylcholine
Arterial Pressure
Vasodilator Agents
Familial Primary Pulmonary Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Loss of reactivity of the pulmonary vascular bed in primary pulmonary hypertension. / Samet, Philip; Bernstein, William H.

In: American Heart Journal, Vol. 66, No. 2, 01.08.1963, p. 197-199.

Research output: Contribution to journalArticle

Samet, Philip ; Bernstein, William H. / Loss of reactivity of the pulmonary vascular bed in primary pulmonary hypertension. In: American Heart Journal. 1963 ; Vol. 66, No. 2. pp. 197-199.
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