LONGITUDINAL CHANGES in CHOROIDAL and RETINAL THICKNESSES in CHILDREN with MYOPIC SHIFT

Peiyao Jin, Haidong Zou, Xun Xu, Ta Chen Chang, Jianfeng Zhu, Junjie Deng, Minzhi Lv, Jiali Jin, Sifei Sun, Ling Wang, Xiangui He

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose:To elucidate the development of the choroid and retina in children, and to explore changes in these during myopic shift.Methods:A total of 118 children aged 7 to 12 years participated in this 1-year longitudinal study. Children underwent several examinations at baseline and follow-up, including cycloplegic refraction, axial length measurement, and swept-source optical coherence tomography. Thickness changes in the choroid and retina were compared among children with or without myopic shift.Results:Eighty-eight children (74.6%) developed a myopic shift after 1 year, and their central foveal choroid was significantly attenuated (P < 0.01). No significant change was observed in choroids of children without myopic shift (P = 0.83). Choroidal thickness decreased in all subfields during myopic shift, whereas the thickness of the retinal layers increased or were unchanged in most subfields. Axial length increase and central foveal choroidal thinning were associated with myopic shift (R2 = 0.157, P < 0.01), but axial length increase was not significantly related to choroidal thinning (P > 0.05).Conclusion:Choroidal thinning occurs early in myopic progression. Axial length increase and choroidal thinning are independently associated with myopic shift.

Original languageEnglish (US)
Pages (from-to)1091-1099
Number of pages9
JournalRetina
Volume39
Issue number6
DOIs
StatePublished - Jun 1 2019

Fingerprint

Choroid
Retina
Mydriatics
Optical Coherence Tomography
Longitudinal Studies

Keywords

  • children
  • choroid
  • myopia
  • retina
  • swept-source optical coherence tomography (SS-OCT)

ASJC Scopus subject areas

  • Ophthalmology

Cite this

LONGITUDINAL CHANGES in CHOROIDAL and RETINAL THICKNESSES in CHILDREN with MYOPIC SHIFT. / Jin, Peiyao; Zou, Haidong; Xu, Xun; Chang, Ta Chen; Zhu, Jianfeng; Deng, Junjie; Lv, Minzhi; Jin, Jiali; Sun, Sifei; Wang, Ling; He, Xiangui.

In: Retina, Vol. 39, No. 6, 01.06.2019, p. 1091-1099.

Research output: Contribution to journalArticle

Jin, P, Zou, H, Xu, X, Chang, TC, Zhu, J, Deng, J, Lv, M, Jin, J, Sun, S, Wang, L & He, X 2019, 'LONGITUDINAL CHANGES in CHOROIDAL and RETINAL THICKNESSES in CHILDREN with MYOPIC SHIFT', Retina, vol. 39, no. 6, pp. 1091-1099. https://doi.org/10.1097/IAE.0000000000002090
Jin, Peiyao ; Zou, Haidong ; Xu, Xun ; Chang, Ta Chen ; Zhu, Jianfeng ; Deng, Junjie ; Lv, Minzhi ; Jin, Jiali ; Sun, Sifei ; Wang, Ling ; He, Xiangui. / LONGITUDINAL CHANGES in CHOROIDAL and RETINAL THICKNESSES in CHILDREN with MYOPIC SHIFT. In: Retina. 2019 ; Vol. 39, No. 6. pp. 1091-1099.
@article{0a779ed268c5414b96020f9b4e1cda62,
title = "LONGITUDINAL CHANGES in CHOROIDAL and RETINAL THICKNESSES in CHILDREN with MYOPIC SHIFT",
abstract = "Purpose:To elucidate the development of the choroid and retina in children, and to explore changes in these during myopic shift.Methods:A total of 118 children aged 7 to 12 years participated in this 1-year longitudinal study. Children underwent several examinations at baseline and follow-up, including cycloplegic refraction, axial length measurement, and swept-source optical coherence tomography. Thickness changes in the choroid and retina were compared among children with or without myopic shift.Results:Eighty-eight children (74.6{\%}) developed a myopic shift after 1 year, and their central foveal choroid was significantly attenuated (P < 0.01). No significant change was observed in choroids of children without myopic shift (P = 0.83). Choroidal thickness decreased in all subfields during myopic shift, whereas the thickness of the retinal layers increased or were unchanged in most subfields. Axial length increase and central foveal choroidal thinning were associated with myopic shift (R2 = 0.157, P < 0.01), but axial length increase was not significantly related to choroidal thinning (P > 0.05).Conclusion:Choroidal thinning occurs early in myopic progression. Axial length increase and choroidal thinning are independently associated with myopic shift.",
keywords = "children, choroid, myopia, retina, swept-source optical coherence tomography (SS-OCT)",
author = "Peiyao Jin and Haidong Zou and Xun Xu and Chang, {Ta Chen} and Jianfeng Zhu and Junjie Deng and Minzhi Lv and Jiali Jin and Sifei Sun and Ling Wang and Xiangui He",
year = "2019",
month = "6",
day = "1",
doi = "10.1097/IAE.0000000000002090",
language = "English (US)",
volume = "39",
pages = "1091--1099",
journal = "Retina",
issn = "0275-004X",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - LONGITUDINAL CHANGES in CHOROIDAL and RETINAL THICKNESSES in CHILDREN with MYOPIC SHIFT

AU - Jin, Peiyao

AU - Zou, Haidong

AU - Xu, Xun

AU - Chang, Ta Chen

AU - Zhu, Jianfeng

AU - Deng, Junjie

AU - Lv, Minzhi

AU - Jin, Jiali

AU - Sun, Sifei

AU - Wang, Ling

AU - He, Xiangui

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Purpose:To elucidate the development of the choroid and retina in children, and to explore changes in these during myopic shift.Methods:A total of 118 children aged 7 to 12 years participated in this 1-year longitudinal study. Children underwent several examinations at baseline and follow-up, including cycloplegic refraction, axial length measurement, and swept-source optical coherence tomography. Thickness changes in the choroid and retina were compared among children with or without myopic shift.Results:Eighty-eight children (74.6%) developed a myopic shift after 1 year, and their central foveal choroid was significantly attenuated (P < 0.01). No significant change was observed in choroids of children without myopic shift (P = 0.83). Choroidal thickness decreased in all subfields during myopic shift, whereas the thickness of the retinal layers increased or were unchanged in most subfields. Axial length increase and central foveal choroidal thinning were associated with myopic shift (R2 = 0.157, P < 0.01), but axial length increase was not significantly related to choroidal thinning (P > 0.05).Conclusion:Choroidal thinning occurs early in myopic progression. Axial length increase and choroidal thinning are independently associated with myopic shift.

AB - Purpose:To elucidate the development of the choroid and retina in children, and to explore changes in these during myopic shift.Methods:A total of 118 children aged 7 to 12 years participated in this 1-year longitudinal study. Children underwent several examinations at baseline and follow-up, including cycloplegic refraction, axial length measurement, and swept-source optical coherence tomography. Thickness changes in the choroid and retina were compared among children with or without myopic shift.Results:Eighty-eight children (74.6%) developed a myopic shift after 1 year, and their central foveal choroid was significantly attenuated (P < 0.01). No significant change was observed in choroids of children without myopic shift (P = 0.83). Choroidal thickness decreased in all subfields during myopic shift, whereas the thickness of the retinal layers increased or were unchanged in most subfields. Axial length increase and central foveal choroidal thinning were associated with myopic shift (R2 = 0.157, P < 0.01), but axial length increase was not significantly related to choroidal thinning (P > 0.05).Conclusion:Choroidal thinning occurs early in myopic progression. Axial length increase and choroidal thinning are independently associated with myopic shift.

KW - children

KW - choroid

KW - myopia

KW - retina

KW - swept-source optical coherence tomography (SS-OCT)

UR - http://www.scopus.com/inward/record.url?scp=85058682750&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85058682750&partnerID=8YFLogxK

U2 - 10.1097/IAE.0000000000002090

DO - 10.1097/IAE.0000000000002090

M3 - Article

C2 - 29517579

AN - SCOPUS:85058682750

VL - 39

SP - 1091

EP - 1099

JO - Retina

JF - Retina

SN - 0275-004X

IS - 6

ER -