Long-term visual outcome in patients with anterior visual pathway gliomas

Gregg S. Gayre, Ingrid U. Scott, William Feuer, Timothy G. Saunders, R. Michael Siatkowski

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Objectives To investigate the visual outcomes of patients with gliomas of the anterior visual pathway and the clinical features associated with prognosis. Materials and Methods During retrospective review, demographic and clinical data were abstracted from medical records of patients seen at the Bascom Palmer Eye Institute between January 1, 1970 and December 31, 1998. Results Of the 42 patients identified, 68% were female, and 55% had neurofibromatosis (NF) type I. There was no substantial difference in presenting signs, symptoms, and visual acuity between the NF(+) and NF(-) groups except for nystagmus, which was more common in the NF(-) group (p = 0.014). Throughout follow-up evaluation, vision in the better eye remained stable in both groups, independent of treatment or NF status. Vision in the worse eye often declined, despite treatment. However, binocular visual status, measured as average weighted logMAR (MAR, minimum angle of resolution) vision, did not change significantly over time, regardless of treatment or NF status. Conclusions In the NF(+) and NF(-) groups, vision in the better eye remained stable, regardless of treatment, and vision in the worse eye often declined, despite treatment. Binocular visual acuity (measured as weighted logMAR) did not change significantly over time, regardless of NF status or treatment modality.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalJournal of Neuro-Ophthalmology
Volume21
Issue number1
DOIs
StatePublished - Jan 1 2001

Keywords

  • Anterior visual pathway
  • Glioma
  • Visual outcome

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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