Long-term T cell lines derived from canine rejecting renal allografts preferentially recognize kidney associated antigens

V. Esquenazi, N. Iglesias, L. Fuller, David Roth, M. Milgrom, L. Olson, J. Miller

Research output: Contribution to journalArticle

Abstract

In order to more clearly examine the effects of anamnestic tissue-associated reactions in the context of transplantation, T cell lines were established from lymphocytes isolated from rejecting canine renal allografts. In the present study, in this canine experimental model, we have characterized the T cell lines with respect to tissue-specific and MHC-disparate immune reactivity. The experimental plan was to study these in vitro reactions, the MLKC, the MLIC, and the mixed lymphocyte pancreatic acinar cell culture (MLAC), each separately described in previous experiments, to determine whether the discrete reactivity of T cell lines exhibited by one reaction is exclusive of the other to further define the specificity, and also to clarify how the reactions are induced.

Original languageEnglish
Pages (from-to)49-51
Number of pages3
JournalTransplantation Proceedings
Volume20
Issue number1 SUPPL. 1
StatePublished - Jan 1 1988

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Allografts
Canidae
T-Lymphocytes
Kidney
Antigens
Cell Line
Lymphocytes
Acinar Cells
Theoretical Models
Cell Culture Techniques
Transplantation
In Vitro Techniques

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Esquenazi, V., Iglesias, N., Fuller, L., Roth, D., Milgrom, M., Olson, L., & Miller, J. (1988). Long-term T cell lines derived from canine rejecting renal allografts preferentially recognize kidney associated antigens. Transplantation Proceedings, 20(1 SUPPL. 1), 49-51.

Long-term T cell lines derived from canine rejecting renal allografts preferentially recognize kidney associated antigens. / Esquenazi, V.; Iglesias, N.; Fuller, L.; Roth, David; Milgrom, M.; Olson, L.; Miller, J.

In: Transplantation Proceedings, Vol. 20, No. 1 SUPPL. 1, 01.01.1988, p. 49-51.

Research output: Contribution to journalArticle

Esquenazi, V, Iglesias, N, Fuller, L, Roth, D, Milgrom, M, Olson, L & Miller, J 1988, 'Long-term T cell lines derived from canine rejecting renal allografts preferentially recognize kidney associated antigens', Transplantation Proceedings, vol. 20, no. 1 SUPPL. 1, pp. 49-51.
Esquenazi, V. ; Iglesias, N. ; Fuller, L. ; Roth, David ; Milgrom, M. ; Olson, L. ; Miller, J. / Long-term T cell lines derived from canine rejecting renal allografts preferentially recognize kidney associated antigens. In: Transplantation Proceedings. 1988 ; Vol. 20, No. 1 SUPPL. 1. pp. 49-51.
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